Aim: This study was conducted to evaluate the impact of different dietary components on gene expression of leptin and adiponectin to understand how nutritional molecules affect gene response and some metabolic pathways in diet-induced obesity in rats. Methodology: Obesity was ind...
Open access
Research Article10.9734/IJBCRR/2016/30489
Aims: The present study investigated the potential nephroprotective activity of aqueous and hydroethanolic extracts of Trema guineensis leaves (Ulmaceae) and determined the most active extract in rat. Study Design: Trema guineensis leaves were collected from Abobo in the district...
Open access
Research Article10.9734/IJBCRR/2016/30539
Aim: Investigating and comparing the effect of administration of different preparations of the commonly-consumed Hibiscus sabdariffa (Zobo) drinks on hepatic and renal indices. Study Design: Animal models (Wistar Albino Rats) with daily administration of the same concentration of...
Open access
Research Article10.9734/IJBCRR/2016/26075
The catalytic activities and kinetic parameters of the enzyme peroxidase (POX), extracted from two plant species namely Rosmarinus officinalis and Eruca sativa, were investigated in the presence and absence of various heavy metals. The activation effects of heavy metals Co2+, Fe3...
Open access
Research Article10.9734/IJBCRR/2016/30399
Aims: This hospital based case-control study sought to analyze the association between the promoter region polymorphism in TNF-α and the risks of developing end stage renal disease in nephropathy subjects. Methodology: 222 documented cases of end stage renal disease (Males=148, F...
Open access
Research Article10.9734/IJBCRR/2016/27911
Assessing the inhibitory activities of Telfairia occidentalis, Murraya koenigii, Hibiscus cannabinus and Vernonia amygdalina on α-amylase with the view of providing a sustainable remedies for the management of diabetes mellitus was conducted. Findings from In vitro studies showed...
Open access
Research Article10.9734/IJBCRR/2016/30494
Aim of the Study: This cross sectional study was aimed to investigate the effect of obesity on vitamin D levels in adult male in the western region of Saudi Arabia. Study Design and Methods: One hundred twenty two Healthy men, aged 20–45 years are included in this study. They wer...
Open access
Research Article10.9734/IJBCRR/2016/30221
Aims: It has been repored that neuropeptide Y receptor Y2 (Y2R) is involved in stress- and high caloric diet-induced metabolic syndrome in mice. Our previous report indicated the association between SNPs of Y2R gene upstream and plasma HDL-cholesterol levels in healthy subjects (...
Open access
Research Article10.9734/IJBCRR/2016/30670
Pawan Kumar Kare, Neerja Aggrawal, Parul Varshney, Rishila Ghosh, Om Prakash Kalra, Basu Dev Banerjee, Sri Venkata Madhu, Vinod Kumar Arora & Ashok Kumar Tripathi·International Journal of Biochemistry Research & Review·2016
Aims: The aim of present study was to find out the prevalence of micro-albuminuria and its relationship with diabetic retinopathy in type 2 diabetes mellitus (T2DM) patients. Study Design: Cross-sectional study. Place and Duration of Study: Department of Biochemistry and Departme...
Open access
Research Article10.9734/IJBCRR/2016/29409
The present research carried out to estimate the antioxidant activity of Anisomeles indica (L.) O. Kuntze leaves by employing some in vitro methods i.e. free radical scavenging activity, reducing ability and chelating ability. The leaves extract showed an excellent activity in al...
Open access
Research Article10.9734/IJBCRR/2016/29720
Background: Cardiovascular diseases (CVD) mortality risk in type 2 diabetes mellitus (T2DM) is a major problem. This study was undertaken to highlight the role of biomarkers network in cardiovascular diabetic complications. Methods: 45 sex and age-matched subjects were included;...
Open access
Research Article10.9734/IJBCRR/2016/29575
This study investigated phytochemical constituents of Nicotiana tabacum (tobacco leaves), its effects on haematological parameters and its histopathology of brain and liver in albino rats. Eighteen (18) male albino rats were divided into three (3) groups with 6 rats in each group...
Open access
Research Article10.9734/IJBCRR/2016/29645
One of cardiovascular diseases, i.e. Diabetes is reported either through absence of insulin or resistance against insulin. Treatment for diabetic disease related to Type 1 and 2 which includes lots of expenditure every year in the form of capsules or preparing different types of...
Open access
Research Article10.9734/IJBCRR/2016/29875
The aim of this study was to explore the peculiarities of the qualitative and quantitative composition of phenolic compounds and antioxidant activity variation in apple (Malus domestica Borkh.) fruit samples during their growth season. The highest total concentration of phenolic...
Open access
Research Article10.9734/IJBCRR/2016/28856
Laminin-1 receptor (40S ribosomal protein SA) and fibronectin-1 belong to the extracellular matrix (ECM) proteins which are involved in cell adhesion, migration and growth. This study was implemented for the purpose of investigating the expression of 40S ribosomal protein SA and...
Open access
Research Article10.9734/IJBCRR/2016/29484