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All published articles 7450

Anti Inflammatory Activity of Musa Sapientum and Its Mediated Copper Nanoparticles- An In Vitro Study

R. Akshaya, S. Balaji Ganesh & S. Rajeshkumar · Journal of Pharmaceutical Research International · 2021

Introduction: Musa sapientum commonly known as ‘banana’ is widely used in Indian folk medicine for the treatment of diabetes mellitus. Copper nanoparticles demonstrate a very strong catalytic activity, a property that can be attributed to their large catalytic surface area. The c...

Open access Research Article 10.9734/jpri/2021/v33i64B35742

Correlation between Level of Functional Ability and Sports Performance among Football Players with Chronic Ankle Instability (CAI)

Shenbaga Sundaram Subramanian, Soon Yuen Teng, P. Senthil, Riziq Allah Mustafa Gaowgeh, Saad Suleman Alfawaz & Ziyad Neamatallah · Journal of Pharmaceutical Research International · 2021

Background: Chronic ankle instability (CAI) is the most common injury among the football players and it occurs with the players who have history of repetitive ankle sprain. This will result in limitation of functional ability and sport performance of a football player. However, m...

Open access Research Article 10.9734/jpri/2021/v33i64B35780

Prevalence of Osteomyelitis in Jaws among the Patients Visiting Private Dental Hospital: An Institutional Study

L. Akshayaa & Pratibha Ramani · Journal of Pharmaceutical Research International · 2021

Introduction: Osteomyelitis is an inflammatory condition of bone that involves the medullary cavity and periosteum. The prevalence rate of this disease was found predominantly among the males than females with an incidence of 30-39 years. This condition involves one or more facia...

Open access Research Article 10.9734/jpri/2021/v33i64B35781

Assessment of the Association between Clinical Examination and Investigations with Outcome in Cases of Abdominal Malignancy

S. Rashmi & S. N. Jajoo · Journal of Pharmaceutical Research International · 2021

Introduction: Abdominal malignancy is a serious problem in the western world which is presently rising in India due to change in lifestyle. The etiopathogenesis are hereditary, environmental and lifestyle factors. The signs and symptoms vary depending upon the type and stage of c...

Open access Research Article 10.9734/jpri/2021/v33i64B35782

Association of Signs and Symptoms at Menarche with Pitta Pre-dominant Prakriti: An Observational Study

Zoya Hasan Khan, Gaurav Sawarkar, Priti Desai, Punam Sawarkar & Amol Deshpande · Journal of Pharmaceutical Research International · 2021

Background: Menarche a sign of puberty which links childhood to adult hood. It is the phase of progression of sexual characters required at the adolescent’s age. It is seen that premenstrual symptoms regularly occurs in luteal phase of menstrual cycle. Similarly, when we can see...

Open access Research Article 10.9734/jpri/2021/v33i64B35797

Incidence of Angular Cheilitis among Patients Visiting Private Dental Hospital in Chennai: An Institutional Study

Anu Iswarya Jaisankar & Pratibha Ramani · Journal of Pharmaceutical Research International · 2021

Introduction: Angular cheilitis is defined as the localised inflammation of the lip commissure. The angles of the mouth are more prone to inflammation as they serve as the points of interface between the squamous epithelium and oral mucosa. It is a multifactorial disease and occu...

Open access Research Article 10.9734/jpri/2021/v33i64B35807

Design and Selection of Novel Kinase Inhibitors Implicated in Alzheimer’s Disease by High Throughput Virtual Screening

Diwakar Sunil Kumar & Singh Anoop · Journal of Pharmaceutical Research International · 2021

CDK5 (cyclin dependent kinase 5) is a promising target for treating a variety of neurodegenerative illnesses. The discovery of effective and selective CDK5 inhibitors that engage the polar side chains of the ATP-binding pocket as well as establish specific hydrogen bonds with the...

Open access Research Article 10.9734/jpri/2021/v33i64B35946

Development and Evaluation of Extended Release Tacrolimus Tablets by Melt Granulation in Combination with Magnesium Alumino Metasilicate

Asif Anwar, Priyanka Soni & Ankit Anand Kharia · Journal of Pharmaceutical Research International · 2021

To increase the effectiveness of tacrolimus, the present study sought to develop extended-release tablets. It is used to treat mild to severe atopic dermatitis as well as to prevent organ rejection after organ transplantation. Tacrolimus, on the other hand, has a poor bioavailabi...

Open access Research Article 10.9734/jpri/2021/v33i64B35978

Prevalence of Joint Hypermobility in Adolescent Females

Poonam Dhankher, Joginder Singh Yadav & Ashish Devgan · Journal of Pharmaceutical Research International · 2021

The joint hypermobility syndrome is a condition that characterises joints that are mobile past the range expected for that particular joint. Hypermobility has a significant impact on quality of life of affected individuals. Hypermobile individuals may be more susceptible to muscu...

Open access Research Article 10.9734/jpri/2021/v33i64B35979

Evaluation of Antiasthmatic Activity of Eraippu Noi Chooranam (ENC)

A. M. Amala Hazel, V. Mahalakshmi, R. Patturayan & R. Meenakumari · Journal of Pharmaceutical Research International · 2021

Background: Every human race has its own traditional system of medicines. Siddha system of medicine is unique and ancient of its kind originating from Tamil Nadu in India. Siddha system could be considered as the crown of all the traditional arts of the ancient Tamil. Eraippu Noi...

Open access Research Article 10.9734/jpri/2021/v33i64B35981

Phytochemical Investigation and Determination of Total Phenols, Flavonoid and Alkaloid Concentration in Leaves Extract of Miliusa tomentosa

Nikhil Brijendra Kumar Shukla, Neeraj Sharma & Shailesh Jain · Journal of Pharmaceutical Research International · 2021

The genus Miliusa (Annonaceae) has over 60 species that are native to India, Bhutan, Australia, and New Guinea, but are mostly found in numerous Asian nations such as Vietnam, Thailand, and China. The growing interest in secondary metabolites' potent biological action highlighted...

Open access Research Article 10.9734/jpri/2021/v33i64B35996

Formulation and Evaluation of Obeticholic Acid Solid Dispersion Tablet

Pawan S. Avhad & Revathi Gupta · Journal of Pharmaceutical Research International · 2021

Obeticholic acid is a farnoside X receptor agonist that was recently licenced by the US Food and Drug Administration. In a solvent, solubility is lower, therefore it is necessary to improve solubility. Solid dispersion is one of the most effective methods for increasing Obetichol...

Open access Research Article 10.9734/jpri/2021/v33i64B36003

Evaluation of Reliability of Various Cephalometric Angles for Assessing Sagittal Jaw Dysplasia in Different Skeletal Pattern: A Cephalometric Study

Swati Vishwakarma, Janis Shajan, Rony T. Kondody, R. N. G. Rajesh, Partha Pratim Roy & S. V. Paramesh Gowda · Journal of Pharmaceutical Research International · 2021

Objective: The study aimed to compare the reliability of different cephalometric angles like the Beta, Yen, W and Pi angles to evaluate sagittal dysplasia in various skeletal patterns and assess the correlation between the variables. Materials and Methods: 135 pre-treatment later...

Open access Research Article 10.9734/jpri/2021/v33i64B36004

Prevalence of Xerostomia among Patients Visiting Private Dental Hospital in Chennai: A Retrospective Study

E. Thariny & Pratibha Ramani · Journal of Pharmaceutical Research International · 2021

Introduction: Xerostomia is a dry mouth condition caused by insufficient or absent saliva flow. Xerostomia is not a disorder, but it may be a symptom of a variety of diseases, a side effect of head and neck radiation, or a side effect of a number of drug medications. It may be li...

Open access Research Article 10.9734/jpri/2021/v33i64B36012

Synthesis and Antimicrobial Activity of Schiff’s and N-Mannich Bases of Indoline 2, 3-Dione and Its Derivatives with N-(4-(4-Aminophenylsulphonyl) Phenyl) Acetamide

Udit N. Soni & Anoop Singh · Journal of Pharmaceutical Research International · 2021

Indoline 2, 3-dione and substituted Indoline 2, 3-dione derivatives were reacted with N-(4-(4-aminophenylsulphonyl) phenyl) acetamide to generate a variety of Schiff's bases. Using these compounds' Mannich bases were created by reacting them with formaldehyde and secondary amine...

Open access Research Article 10.9734/jpri/2021/v33i64B36014