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All published articles 7450

Efficacy and Safety of Lebrikizumab in Atopic Dermatitis: A Systematic Review and Meta-analysis

Mohammed Abdullah Alahmadi, Khadeeja Ali Hamzah, Eathar Haidar Aljubori, Dalia Dhia Hadi, Marwa Mohammed Saleh Tuke, Mohamed Ellebedy, Juman Alammar, Ghadir Ali Alkhfash & Haydar Raheem Hmoud Al-Saaidy · Journal of Pharmaceutical Research International · 2024

Background: Atopic Dermatitis (AD) is a long-lasting dermatological condition that leads to skin irritation and inflammation. In cases of severe cases of AD biological therapy may be warranted. In this systematic review and meta-analysis, we aim to assess the efficacy and safety...

Open access Research Article 10.9734/jpri/2024/v36i117610

Analytical Method Developement and Validation of Beclomethasone, Clotrimazole, Ofloxacin, Lidocaine by RP-HPLC in Combination Dosage Form

Dinesh P. Borkar, Anup Barsagade, Nobel CP James, Suruchi Thakare & Susmita Mandal · Journal of Pharmaceutical Research International · 2024

A rapid and precise method (in accordance with ICH guidelines) is required for the quantitative simultaneous determination of drugs in a combined pharmaceutical dosage form. The pursuit of desired quality is a continual challenge for pharmaceutical industries, necessitating a met...

Open access Research Article 10.9734/jpri/2024/v36i117609

The Silent Struggle: Addressing Post-COVID Health Challenges with Booster Doses

Mahbuba Khatun, Shohal Hossain, Shahnaz Rahman, Md. Abu Rayhan, Md. Nafij Mashrur, Md. Fuad Hossain, Asma Farid, Nahin Islam Lammi, Mostafa Tanvir Tusar, Md. Kamrul Hasan Jabed Chowdhury & Mst. Sumi Islam · Journal of Pharmaceutical Research International · 2024

Background: Coronavirus Disease-19 (COVID-19) primarily an infectious disease of respiratory tract caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2), it has triggered the rapid expanding pandemic worldwide, including in Bangladesh and has left deep impact on...

Open access Research Article 10.9734/jpri/2024/v36i117608

Hepatoprotective Investigation of Ficus lyrataand Ficus elastic Leaves Extract

Mrinal Aryan, Ashish Manigauha & Vishal Gupta · Journal of Pharmaceutical Research International · 2024

In hepatotoxic Albino rats caused by isoniazid and paracetamol, the hydroalcoholic extract of Ficus lyrata and Ficus elastic leaves was evaluated for hepatoprotective activity. The degree of protection was measured by estimating biochemical parameters such as serum glutamate Oxal...

Open access Research Article 10.9734/jpri/2024/v36i117606

Exploring the Complex Relationship between Psychological Stress and Fertility: Implications for Population Growth in Developing Countries

Imtiyaz Alam & Praveen Chander · Journal of Pharmaceutical Research International · 2024

Uncontrolled population growth has raised serious concerns among future policymakers. Although fertility rate has declined substantially over time, in developing countries the rate is still very high. Most of these countries face serious issues such as; severe poverty, malnutriti...

Open access Research Article 10.9734/jpri/2024/v36i117607

Therapeutic Evaluation of Various Antibiotics Use in Paediatric Inpatients: Insights from a Tertiary Care Teaching Hospital

Bala Teresa K, Mohammed Abrar, Vaidurya S Padman, Varshini V Reddy, Sameera Shabnam, Jemimah Mary Jomon & Nagarjuna D · Journal of Pharmaceutical Research International · 2024

Background: Antimicrobial consumption has led to the development of antimicrobial resistance, a major concern to the healthcare system as it has severe consequences, including loss of life. Antimicrobial resistance predicts 4.7 million deaths in Asia by 2050. Objective: To reduce...

Open access Research Article 10.9734/jpri/2024/v36i117604

Innovations in Drug Delivery: From Microtechnology to Targeted Therapeutics

Muhammad Abid Mustafa, Namra Rasheed, Hamza Ghauri, Muhammad Obaidullah Shahzad, Ameer Hamza, Muhammad Hasnat Rafique, Minahil Nasir, Mavra Siddique, Wasta Aslam Gill & Syed Taimoor Tayyab · Journal of Pharmaceutical Research International · 2024

Drug delivery systems are developed to maximize drug efficacy and minimize side effects. As drug delivery technologies improve, the drug becomes safer and more comfortable for patients to use. The study on advanced drug delivery systems aims to increase patient compliance, decrea...

Open access Research Article 10.9734/jpri/2024/v36i117605

Emerging Protein and Peptide Therapeutics for Osteoporosis: Advances in Anabolic and Catabolic Treatments

Akhilesh Kumar Kuril, Krishna Moorthy Manchuri & Swapnil Prakash Anand · Journal of Pharmaceutical Research International · 2024

Osteoporosis is a prevalent skeletal disorder characterized by reduced bone density and increased fracture risk, primarily affecting the elderly population. The pathophysiology of osteoporosis involves an imbalance between bone resorption and bone formation, with catabolic proces...

Open access Research Article 10.9734/jpri/2024/v36i117603

Pharmacists Attitude and Perceived Barriers toward Providing Vaccination Services

Abu Sufiyan Ali, Ahmad Hanan Shah, Ahmad Safiyan, Malaika Ijaz, Hammad Ali Bhatti, Tabinda Razzaq & Muhammad Zahid Iqbal · Journal of Pharmaceutical Research International · 2024

Background: Vaccination has significantly reduced the global burden of infectious diseases, preventing millions of deaths annually. Despite the availability of effective vaccines, suboptimal vaccination coverage remains a challenge, limiting the full realization of vaccination be...

Open access Research Article 10.9734/jpri/2024/v36i117600

Pharmacist’s Knowledge and Attitudes toward Digital Health Tools

Aila Khan, Ghanwa Fatima, Aima Subia Alvi, Aqsa Jamil, Iqbal Bibi, Talha Rehman & Muhammad Zahid Iqbal · Journal of Pharmaceutical Research International · 2024

Background: Digital health solutions have seen a remarkable increase in recent years as they enhance the efficiency and effectiveness of healthcare system. Digital health tools have transformed how patients interact with healthcare. Digital health tools help in diagnosis, measuri...

Open access Research Article 10.9734/jpri/2024/v36i117601

Assessment of Knowledge, Attitudes and Practices among Community Pharmacists in Lahore Regarding Prescription Patterns in Children: A Cross Sectional Study

Sumbal Rafique, Muskan Islam, Muhammad Sheraz, Hamza Ghauri, Noor-ul-Ain, Irsa Irshad, Shuja Ur Rehman Khan, Muhammad Obaidullah Shahzad, Muhammad Sameer, Ahmad Sarfaraz & Muhammad Zahid Iqbal · Journal of Pharmaceutical Research International · 2024

Background: Community pharmacists play a vital role in ensuring that pediatric patients utilize drugs safely and effectively. Pediatric patients require special attention. To identify possible gaps in their knowledge of proper dosage, formulation selection, pharmacists' knowledge...

Open access Research Article 10.9734/jpri/2024/v36i117602

High-Throughput Insilico Drug Screen against Mpox Targeted Proteins in Comparison with Repurposed Antiviral Drugs against Natural Compounds

Hemanth Kumar Manikyam, Sandeep Balvant Patil, Nazim Hussain, R. Edison Eegai Vallal, Shikha Sharma & Abhinandan Ravsaheb Patil · Journal of Pharmaceutical Research International · 2024

The recent resurgence of the Monkeypox Virus (MPXV) has prompted increased efforts to discover effective antiviral treatments. This study utilized an in silico docking approach with CB Dock2 to assess both natural compounds and repurposed antiviral medications. We concentrated on...

Open access Research Article 10.9734/jpri/2024/v36i117599

Phytochemical Screening and Safety Assessment of a Polyherbal Tea Formulation of Lippia Multiflora, Zinger Officinale and Mentha Piperita

N'DRI Quesnelle Epiphanie, Kporou Kouassi Elisée, Ouattara Sitapha, Beugre Avit Grah Maxwell & KOUAKOU-SIRANSY Gisèle · Journal of Pharmaceutical Research International · 2024

Aims: Lippia multiflora, Zingiber officinale, and Mentha piperita are aromatic plants known for their health benefits. This study the phytochemical composition and evaluate the safety of a tea made from them for safe human consumption. Methodology: For tea formulations, powder of...

Open access Research Article 10.9734/jpri/2024/v36i117598