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Neck Circumference, a Screening Tool for Obesity in Newly Pubescent Children-A Case Study

M. Ponmalar, S. Rajini & V. Tamilsevi · Journal of Pharmaceutical Research International · 2021

“Childhood Obesity and its co-morbidities is considered as a prime health hitch that lay up consideration among the public health society. Obesity and above the over weight has bagged the fifth position in the global risk for mortality. The obesity shows a very early onset in lif...

Open access Research Article 10.9734/jpri/2021/v33i44A32645

A Study to Assess the Effectiveness of Token Economy for Behavior Problems among Mild and Moderate Mentally Challenged Children in Selected Special Homes

A. R. Bharathi · Journal of Pharmaceutical Research International · 2021

This study was conducted to evaluate the Effectiveness of Token Economy on Behavioural Problem among Mentally Challenged Children in a Selected Special homes, Chennai. In this study Pre Experimental (one group pre test- post test) design was adopted. Setting of the study was Math...

Open access Research Article 10.9734/jpri/2021/v33i44B32646

Human Serum Albumin: A Novel Drug Delivery Carrier System

Snehal Patel, Chintan Aundhia, Avinash Seth, Nirmal Shah, Dipti Gohil & Kartik Pandya · Journal of Pharmaceutical Research International · 2021

Serum albumin, often referred to simply as albumin, is a globular protein that in humans is encoded by the ALB gene. Albumin is a multifaceted, highly soluble, stable, nontoxic, non-poisonous, biocompatible and biodegradable plasma protein. Albumin has been widely studied as a pr...

Open access Research Article 10.9734/jpri/2021/v33i44B32648

A Rare Case of Pansinusitis Fungal Mucormycosis with Orbital Involvement in Post COVID-19 Patient and Its Treatment

Deepali Ghungrud, Ranjana Sharma, Seema Singh & Ruchira Ankar · Journal of Pharmaceutical Research International · 2021

Introduction: Covid-19 pandemic disease and its infections caused may be associated with bacterial and fungal co-infections. Case Presentation: A 61- year-old male patient, after Covid-19 disease admitted in hospital with the complaints of headache, right eye swelling, watering o...

Open access Research Article 10.9734/jpri/2021/v33i44B32656

Comparative Phytochemical Profiling of Garlics (Allium sativum L.) and Onion (Alium cepa L.)

Siti Nor Aisyah Mohd Zawawi, Nurul Izzati Osman, Ibtisam Abdul Wahab & Hannis Fadzillah Mohsin · Journal of Pharmaceutical Research International · 2021

Aims: This research aims to perform the extraction of garlic samples and onion as well as to carry out qualitative phytochemical screening by using Thin Layer Chromatography (TLC) and phytochemical analyses for the detection of carbohydrates, flavonoids, and alkaloids.  Study Des...

Open access Research Article 10.9734/jpri/2021/v33i44B32647

Self-Medication with Antibiotic among Public Population in Erbil City

Rozhan Arif Muhammed, Ahmed Habeeb Hattab Dala Ali Al-Ani & Ali Omar Yassen · Journal of Pharmaceutical Research International · 2021

Self-medication is the administration of medications without a medical prescription to manage self-diagnosed health problems or symptoms. Self-medication with antibiotics is a global phenomenon, and it is more common in developing countries due to poor regulatory controls. The ai...

Open access Research Article 10.9734/jpri/2021/v33i44B32649

Designing of some Novel Methyl 2-((4-(Benzamido)Phenyl)Sulfanyl)-1,2,3,4-tetrahydro-6-Methylpyrimidine-5-carboxylate Derivatives as Potential Glucokinase Activators through Molecular Docking

A. A. Kazi & V. A. Chatpalliwar · Journal of Pharmaceutical Research International · 2021

Aims: Glucokinase (GK) is a cytoplasmic enzyme that metabolizes the glucose to glucose- 6-phosphate and supports the adjusting of blood glucose levels within the normal range in humans. In pancreatic β-cells, it plays a leading role by governing the glucose-stimulated secretion o...

Open access Research Article 10.9734/jpri/2021/v33i44B32650

Fixed Dose Formulation Development and Evaluation of Bilastine and Montelukast Sodium Tablets

Umesh Chandra, Manish Kumar, Arun Garg, Shrestha Sharma & Pankaj Gupta · Journal of Pharmaceutical Research International · 2021

Aim: The present research work was carried out to formulate stable fixed dose combination tablets of Bilastine and Montelukast Sodium, used to treat allergic rhinitis associated with asthma and rhino-conjunctivitis on basis of pre and post post-compression parameters evaluation a...

Open access Research Article 10.9734/jpri/2021/v33i44B32651

A Cross-sectional Study to Assess the Risk of Diabetes Mellitus among Pre-diabetes Obese People of Selected Rural Area of Waghodia Taluka, Vadodara

S. Adithya, C. Ranganatha & M. Gayathri · Journal of Pharmaceutical Research International · 2021

Background: India is the diabetic capital of the world, with a maximum number of diabetic patients. There is a large burden of undetected diabetic cases in the community. There is an increasing risk of diabetes in urban slums and rural areas, because of illiteracy, lack of awaren...

Open access Research Article 10.9734/jpri/2021/v33i44B32652

Expression of ITG β-1, MMP9 and Vimentin in Oral Squamous Cell Carcinoma – A Real Time PCR Based Approach

Krishnapriya Umashankar, J. Selvaraj & Pratibha Ramani · Journal of Pharmaceutical Research International · 2021

Background: Oral Squamous Cell Carcinoma (OSCC) is the most common malignancies which accounts for 90% of oral cancer worldwide. The 5 year survival rate of OSCC is not more than 60% due to tumor metastasis and subsequent recurrence. Aim: To compare the gene expression of ITG β-1...

Open access Research Article 10.9734/jpri/2021/v33i44B32653

A Simple and Sensitive LC-MS/MS Method for Determination and Quantification of Potential Genotoxic Impurities in the Vismodegib Active Pharmaceutical Ingredient

Rayala Rama Rao, Gundapaneni Ravi Kumar, Vadde Megha Vardhan & Veeraswami Boddu · Journal of Pharmaceutical Research International · 2021

A rapid and sensitive LC-tandem mass spectrometry (LC-MS/MS) method was developed and validated for the quantitative analysis of four potential genotoxic impurities Imp-A (2-chloro-5-nitroaniline), Imp-B (1-chloro-2-iodo-4-nitrobenzene), Imp-C (1-(2-chloro-5-nitrophenyl)ethan-1-o...

Open access Research Article 10.9734/jpri/2021/v33i44B32654

Compounds from Vernonia arborea Buch.-Ham. Inhibit Microbes that Impair Wound Healing

Lalitha Vaidyanathan & T. Sivaswamy Lokeswari · Journal of Pharmaceutical Research International · 2021

Aims: To identify the antimicrobial potency of the leaf fractions of Vernonia arborea against selected wound microbes viz., Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumoniae and Stenotrophomonas maltophilia. Background: Wound healing is often...

Open access Research Article 10.9734/jpri/2021/v33i44B32655

Diagnostic Accuracy of Magnetic Resonance Cholangiopancreatography (MRCP) In-Patients Undergoing Endoscopic Retrograde Cholangiopancreatography (ERCP) for Pancreaticobiliary Disorders

M. Vignesh Kumar · Journal of Pharmaceutical Research International · 2021

This is a prospective study done to compare the diagnostic accuracy of Magnetic Resonance Cholangiopancreatography (MRCP) in patients undergoing Endoscopic Retrograde Cholangiopancreatography (ERCP) for pancreaticobiliary disorders.Majority of the study participants were males (6...

Open access Research Article 10.9734/jpri/2021/v33i44B32657

Assessment of the Psycho Social Problems Related with Obese Juveniles in Actual Government School at Chennai

A. R. Bharathi · Journal of Pharmaceutical Research International · 2021

To evaluate the level of obesity, associated psychosocial problems and comparison with demographic variables in a selected government school at Chennai. Stock (1974) health belief Theory, a non-experimental study design, was used as the conceptual frame work in the present study....

Open access Research Article 10.9734/jpri/2021/v33i44B32658

Prevalence of Genotype 3a in Different Regions of Pakistan: A systematic Review and Meta-Analysis

Rehan Ahmad Khan Sherwani, Maria Aslam, Kanwal Saleem, Atif Khan Jadoon & Hafiz Muhammad Nawaz · Journal of Pharmaceutical Research International · 2021

The present study aims to explore the prevalence of genotype 3a under hepatitis C virus (HCV) infections among all the provinces of Pakistan. It is alarming to note that Pakistan stands in the second position for having a large number of cases of HCV every year. Six major genotyp...

Open access Research Article 10.9734/jpri/2021/v33i44A32628