This study was aimed to determine the in-vitro optimum conditions of xylanase enzyme activity produced by Orpinomyces sp. and Neocallimastix sp. In the study, xylanase enzyme activity was investigated in terms of extracellular and intracellular total activity (TA) and specific ac...
Open access
Research Article10.9734/jpri/2022/v34i51A36443
Faryal Javed, Summiya Zubair, Hassan Imran, Safia Sultana Munir, Humayun Riaz, Misbah Sultana, Ruqaiya Rasheed Kayani, Saba Manzoor, Saeed Ur Rashid Nazir & Muhammad Maaz Ali·Journal of Pharmaceutical Research International·2022
Mutation in several factors and pathways leads to the development of hepatic cancer i.e. Mutation in Wnt-β-Catenin Signalling Pathway , activation of the Insulin-Like Growth Factor (IGF) Signalling Pathway, The P13/PTEN/AKT, TP53 Tumour Suppressor Gene. Liver cirrhosis and fatty...
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Research Article10.9734/jpri/2022/v34i50B36441
Aims: Catunaregam spinosa is an exotic plant in Sri Lanka. Fruits of this plant contain saponins, steroids, flavonoids possessing piscicidal property. Since years ago C. spinosa employs in the fishery industry, especially in rural areas. This study was established to evaluate the...
Open access
Research Article10.9734/jpri/2022/v34i50B36440
In response to shifting consumer demands, food packaging's conventional function is continuing to change. Consumer desire for healthier, safer and good quality meals with longer shelf-life is one of the current causes that are challenging the food packaging sector to produce new...
Open access
Research Article10.9734/jpri/2022/v34i50B36439
The ever-increasing fatality due to the surge of drug resistance has demanded the development of therapeutic metabolites with novel modes of mechanism. Despite the discovery of new antimicrobials, antibiotic resistance is increasing at an alarming rate. The emergence of novel mol...
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Research Article10.9734/jpri/2022/v34i50B36438
Current published scientific works on human neutrophils have shown them to be heterogeneous in their immune functions. Activated neutrophil perform both up regulation and down regulation processes on other immune cells finalized by either tissue protection or tissue damage in vir...
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Research Article10.9734/jpri/2022/v34i50B36437
Introduction: The horizontal position of upper and lower lips have been of great concern when planning a treatment plan of an orthodontic patient, because the purpose of orthodontic treatment is to establish an esthetic facial profile and not just a functional occlusion. Objectiv...
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Research Article10.9734/jpri/2022/v34i50A36436
Aim: Natural products which are gradually gaining importance because of its medicinal value in clinical research due to their well-known property of fewer or no side effects as compared to synthetic drugs. World Health Organization also advised the general public to focus on enha...
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Research Article10.9734/jpri/2022/v34i50A36435
Most scholars regard mixed connective tissue disease (MCTD) to be a separate illness, whereas some suggest it might be a precursor to a distinct connective tissue disease, such as SLE, SSc, or overlap syndrome. There are no distinct clinical symptoms of MCTD, and clinical present...
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Research Article10.9734/jpri/2022/v34i50A36434
The number of 88 rats was chosen, after 21 days, they were ablactated and categorized them as following groups: The control group 1 has a cage of 8 rats in a social condition. After 6 weeks of saline injection (1mg / kg), the yawning behavior is recorded for 60 minutes. Group 2 i...
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Research Article10.9734/jpri/2022/v34i50A36433
Aim: To evaluate the pharmacological effects of pumpkin seeds in correlation to weight gain in rabbits. Methodology: After observing as standard inclusion and exclusion criteria, thirty healthy adult rabbits recommended in study. Calculated amount 250 mg and 500 mg of powder of p...
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Research Article10.9734/jpri/2022/v34i49B36431
Introduction: Taste buds are the peripheral organs of gustation and are located mainly in the tongue epithelium and palate. Taste buds further sample the chemical makeup of foods and beverages for nutrient content, palatability, and potential toxicity. On the other hand, the smel...
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Research Article10.9734/jpri/2022/v34i50A36432
Aim: This work aims to develop oral disintegrating tablets from solid dispersion of aripiprazole that are capable of enhancing solubility. Methodology: Aripiprazole an antipsychotic is a BCS class IV drug with Oral bioavailability of 87%. To enhance the solubility of this drug th...
Open access
Research Article10.9734/jpri/2022/v34i49B36429
Chibuike Ernest Ikwuka, Chukwuebuka Moses Asogwa, Ozioma Jennifer Ikwuka, Jude Ebuka Ogbonna, Chinwe Mercy Onah, Christian Chukwuagozie Ohama & Charles Okeke Nnadi·Journal of Pharmaceutical Research International·2022
Aims: To evaluate the antiplasmodial activity of a trisdimethylamino pyrimidine derivative synthesized by indirect methylation of p-nitrophenylacetic acid via a substituted amine or amide derivative against Plasmodium berghei NK65 strain in an in vivo Plasmodium berghei-Infected...
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Research Article10.9734/jpri/2022/v34i49B36430
Background: The relationship between sleep disturbance and diabetes is dual-sided. Chronic sleep disturbance increases the chance of developing insulin resistance, while diabetes reduces sleep quality. Objective: To address the aspects of insufficient sleep, diabetes mellitus, an...
Open access
Research Article10.9734/jpri/2022/v34i49B36427