Aims: The purpose of this study was to determine the cell viability and cytotoxicity of various endocytosis and efflux inhibitors which can be used to determine transport and uptake mechanisms in the BeWo (b30 clone) human placental trophoblast cell line. Ethanol and dimethylsulf...
Open access
Research Article10.9734/JPRI/2017/34606
Background: The burden of illness is increasingly tending towards chronic diseases while medication adherence is often unsatisfactory. The patient information leaflet is one model that has the prospect to improve medication adherence. Improving the readability and content based v...
Open access
Research Article10.9734/JPRI/2017/34603
Aim: This study focused on evaluation of the anti-bacterial effects and synergism of Faradin®), a polyherbal complementary alternative medicine (CAM) and anti-sickling agent. It is used for treatment of sickle cell disease (SCD) and co-morbidities (such as infection and inflammat...
Open access
Research Article10.9734/JPRI/2017/33606
Aims: An in-depth study on the phytochemical contents, antimicrobial and antioxidative activities of stem tissue of Derris trifoliata Lour. (Fabaceae), a mangrove shrub from Sundarban estuary, India. Methodology: Phytochemical analyses were carried out using established methods f...
Open access
Research Article10.9734/JPRI/2017/34455
Background: The prevalence of hyperuricemia and gout had shown an increasing trend all over the world including in developing countries. The patients may receive very little education on the dietary and lifestyle factors associated with gout. Objective of the Study: Assess knowl...
Open access
Research Article10.9734/JPRI/2017/34375
The aim of the current study was to investigate the nephroprotective effect of Punica granatum peel (pomegranate) against gentamicin induced nephrotoxicity. The crude pomegranate peel (600 mg/kg) and methanolic pomegranate extract (600 mg/kg) for 7 days showed significant (p<0...
Open access
Research Article10.9734/JPRI/2017/34616
Aim: This study aims at investigating the emulsifying properties of Cucumis sativus mucilage, compare with gelatin and tragacanth with further assessment of their combined effects on the emulsion properties. Place and Duration of Study: Department of Pharmaceutics and Pharmaceuti...
Open access
Research Article10.9734/JPRI/2017/34465
This study was designed to examine the hypoglycemic and antioxidant defense by methanolic extract of Zingiber officinale on alloxan induced diabetes in Wistar rats.The preliminary study showed that Z. officinale extract was able to scavenge the 2,2-Diphenyl-1-picrylhydrazyl (DPPH...
Open access
Research Article10.9734/JPRI/2017/34396
Aims: Diabetes mellitus is characterized by hyperglycemia, which leads to acceleration of protein glycation. Some glycation products form inter molecular cross-links, contributing to chronic diabetic complications. Determination of protein glycation inhibitory potential of medici...
Open access
Research Article10.9734/JPRI/2017/34049
Background: Hypertension is the commonest cardiovascular risk factor encountered in Cardiology Clinics in Nigeria. The aim of this study was to assess the prescribing pattern of antihypertensive medications and conformity to guidelines by physicians at the Cardiology Clinic of Fe...
Open access
Research Article10.9734/JPRI/2017/33841
The study assessed molecular interactions between the actives in antimalarial dihydroartemisinin-piperaquine (DP) tablet and food components using Fourier transform infrared spectroscopy (FTIR). Soluble starch, lactose, albumin, sunflower oil and carbonated drinks were pelletized...
Open access
Research Article10.9734/JPRI/2017/28516
Aim: This study was conducted to investigate the preventive or therapeutic effect of α-glucosidase inhibitor voglibose in a new model rat, Spontaneously Diabetic Torii-Leprfa (SDT fatty) rat, which is a novel type 2 diabetic rat showing obesity, hyperglycemia and hyperlipidemia f...
Open access
Research Article10.9734/BJPR/2014/13553
Background: Common cold is a self limited viral infection, which can be treated symptomatically without the need to antibiotics which are not effective or curative. This study aimed to evaluate the practices of community pharmacists in communicating, diagnosing, treating and coun...
Open access
Research Article10.9734/BJPR/2014/13586
The seeds of Cola nitida were investigated for their anti-diabetic properties. The extracts were obtained by maceration in cold water. Alloxan was used to induce diabetes mellitus (DM) in the rats at 180mg/kg body weight and diabetes was confirmed after 48 hours. The Phytochemica...
Open access
Research Article10.9734/BJPR/2014/13071
Aims: This study explores the total quantity of sulfur secondary metabolites in the plant organs of garlic and ramsons, the content of total phenol and their correlation to the antioxidant capacity (AOC). There are different reports about correlation of secondary sulfur compounds...
Open access
Research Article10.9734/BJPR/2014/13977