Aims: The study is aimed at gaining a better understanding of the perception of in-patients on the pharmaceutical care (PC) roles of pharmacists. This is useful in assessing the quality of care provided by the pharmacist and in the design and implementation of improved PC program...
Open access
Research Article10.9734/BJPR/2014/10222
What is it? Darunavir is a protease inhibitor used in the treatment of HIV infection. It is an important drug of therapy cocktail for patients infected with the virus. On the market there are darunavir ethanolate tablets of 75, 150, 300, 400, 600 and 800mg, because this is the mo...
Open access
Research Article10.9734/BJPR/2014/7607
Aims: This study was undertaken to investigate the antioxidant effects of atorvastatin in treating cases of atherosclerosis associated with hyperlipidemia. Methodology: Forty local domestic rabbits were assigned to five groups (eight rabbits in each group): After two weeks acclim...
Open access
Research Article10.9734/BJPR/2014/10140
Tatiane Bezerra de Oliveira, Carlson Helder Reis de Carvalho Júnior, Fernanda Virgínia Barreto Mota, Larissa Cardoso Corrêa de Araújo, Maria Bernadete Sousa Maia, Karina Perrelli Randau, Silene Carneiro do Nascimento & Teresinha Gonçalves da Silva·Journal of Pharmaceutical Research International·2014
Aims: This paper describes the anti-inflammatory and antinociceptive effects of the aqueous extract of Chrysobalanus icaco. Study Design: Study the anti-inflammatory and antinociceptive activity of the aqueous extract of C. icaco using in vivo models. Place and Duration of Study...
Open access
Research Article10.9734/BJPR/2014/8742
Aims: The present study was carried out to evaluate Amlodipine, a L-type calcium channel blocker for alleviating or reducing the neurodegeneration in 6-OHDA lesioned rat models. Place and Duration of Study: Department of Pharmacology, JSS College of Pharmacy, Rocklands, Ooty, Ind...
Open access
Research Article10.9734/BJPR/2014/6613
Mosaad A. Abdel-Wahhab, Ahmed A. El-Kady, Olivier Joubert, Aziza A. El-Nekeety, Yong T. Kim, Won J. Yoon, Myung H. Park & Bertrand H. Rihn·Journal of Pharmaceutical Research International·2014
Aim: The aim of this study was to evaluate the effects of Panax ginseng extract standardized with ginsenoside Rg3 (PGRg3) on the mating behavior of sexually active or inactive male rats treated with dopamine antagonists. Methodology: Animals were treated with PGRg3 (50,150 and 45...
Open access
Research Article10.9734/BJPR/2014/9673
Aims: To determine the survival rates of bacteria in contaminated fresh fruit juice samples Place and Duration of Study: Biosciences and Biotechnology Department, Babcock University, Ilisan Remo, Ogun State, Nigeria, between November, 2012 and May, 2013. Methodology: Freshly extr...
Open access
Research Article10.9734/BJPR/2014/7384
Pitchaipillai Revathi, Thalaimalai Senthinath Jeyaseelan, Madhavan Vigneshwari, Nagarajan Prabhu, Mayilsamy Nithya, Subramaniya Pillai Manickavasagam, Alagappan Uma & Ponniah Thirumalaikolundusubramanian·Journal of Pharmaceutical Research International·2014
Aims: To monitor the antimicrobial utilization; identify the preferred group of antibiotics in outpatient services, determine the prescribing pattern of antibiotics by consultants in a rural teaching hospital, evaluate the inappropriate usage of antibiotics among population and e...
Open access
Research Article10.9734/BJPR/2014/9961
Aim: To evaluate the acute and sub-acute toxicities of Raphia hookeri (Rh) seed hydroethanolic extract on experimental animals. Materials and Methods: Acute toxicity study was evaluated on Swiss albino mice of both sexes. Administration of a single dose of 4000mg/kg of Rh seed ex...
Open access
Research Article10.9734/BJPR/2014/9330
Objective: This study aims to develop controlled release buccal tablets of losartan potassium based on bioadhesion using direct compression technique. Materials and Methods: The bioadhesive buccal tablets of losartan potassium were prepared after preliminary drug-excipients compa...
Open access
Research Article10.9734/BJPR/2014/9789
Rosuvastatin-Ca was prepared in solid dispersion as buccoadhesive tablets to increase its bioavailability and the release of the drug from its buccoadhesive formulae due to its poor aqueous solubility. The solid dispersions were prepared using β-cyclodextrin, polyethylene glycol...
Open access
Research Article10.9734/BJPR/2014/9257
Aim: In the present study, Sumatriptan succinate was formulated as oral elementary osmotic pump with a zero-order drug release profile. Methodology: The effect of different formulation variables i.e. different types of osmogens, concentrations of osmogen and concentration of coat...
Open access
Research Article10.9734/BJPR/2014/8666
Aims: To investigate the influence of appropriate culture medium by optimizing the cultural conditions affecting the growth and bioactive metabolite production by Streptomyces gulbargensis DAS 131 under submerged culture conditions in order to reduce the cost of fermentation proc...
Open access
Research Article10.9734/BJPR/2014/7085
Back Ground and Objectives: Despite the therapeutic benefits of cisplatin (CDDP), its use clinically is often limited due to dose-related nephrotoxicity. On the meanwhile, DPP 4 inhibitors could attenuate kidney injury, so in the present work, it was aimed to investigate the effe...
Open access
Research Article10.9734/BJPR/2014/9297
Background: Decaying stem juice of Musa acuminata × balbisiana is commonly used by local communities and traditional herbalist in Central Uganda in the management of cardiovascular conditions like hypertension. Aims: The study investigated the ionotropic and chronotropic effect o...
Open access
Research Article10.9734/BJPR/2014/6529