Chlorambucil (CLB) is an aromatic nitrogen mustard and an alkylating agent. It has been mainly used in the chemotherapy. A method for radiopharmaceutical preparation of [125I]-iodo-Chlorambucil a potential cancer therapeutic agent is described. The method is based on direct elect...
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Research Article10.9734/BJPR/2014/10520
Background: A “near miss” or close call is a medication error that happened but did not result in injury or damage to the patient. These medication errors (MEs) are captured and corrected before affecting the patient either fortuitously or purposefully by designed system controls...
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Research Article10.9734/BJPR/2014/8607
Aim: The aim of this study is to determine the effect of aqueous extract of Psidium guajava leaf on blood glucose level and liver enzymes of alloxan –induced diabetic rat. Study Design: The animals were grouped into six of 6 rats each. Groups A, B, C and E were induced diabetes b...
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Research Article10.9734/BJPR/2014/7244
Aims: Adenium obesum is a known medicinal plant thereby creating the need for the evaluation of its toxicity and histopathological effects on the liver of female Wistar rats orally administered ethanol extract of the plant’s stem bark. Place and Duration of Study: Department of V...
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Research Article10.9734/BJPR/2014/7667
Aim: The aim of this study was to evaluate the synergistic effect of low radiation dose with the chemotherapeutic drug in order to find possible way to lessen the harmful effects during chemo-radiotherapy. Study Design: Randomized controlled experiment. Place and Duration of Stud...
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Research Article10.9734/BJPR/2014/8980
Aims: The purpose of this study is to assess and confirm the ameliorative effects of alcohol consumption on biochemical indices of blood i.e., blood glucose, HbA1c, NO2, NO3, lipid profiles, hs-CRP (high sensitive C–Reactive protein) and membrane lipid peroxidation of diabetics....
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Research Article10.9734/BJPR/2014/4857
Aims: The aim of the present study was to develop an emulgel formulation of Clotrimazole using carbopol 934 or hydroxyl propyl methyl cellulose 2910 as a gelling agent. The influence of the type of gelling agent and the concentration of both the oil phase and the emulsifying agen...
Open access
Research Article10.9734/BJPR/2014/8495
Objective: To investigate the antihyperglycemic and antioxidant properties of the petroleum ether extract of Ocimum canum leaves in streptozotocin-induced diabetic rats. Place and Duration of Study: Pinacle Biomedical Research institute (PBRI), Bhopal april 2013-december 2013. Me...
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Research Article10.9734/BJPR/2014/8782
Aims: To screen the hepatoprotective and antioxidant activity of ethanol extract of roots of Valeriana wallichii DC (Valerianaceae)(VWE). Study Design: Animal study. Place and Duration of Study: Department of Pharmacology, Biochemistry and Anatomy (Histology section), J N Medical...
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Research Article10.9734/BJPR/2014/7378
Prescribing multiple medications predisposes to possibilities of occurrence of drug interactions. Various different terminology and ways exist to classify or arrange drug interactions. Drugs interact with other drugs, foods, beverages and herbs; outside or inside the body. Knowle...
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Research Article10.9734/BJPR/2014/8531
Aims: The objective of this study is to evaluate the effects of adding two different glucans coded as BGO1 and BGO2 into commercial feed of dogs. Study Design: We measured changes in phagocytosis, levels of IL-2 in blood, antibody formation and level of blood sugar (normal homeos...
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Research Article10.9734/BJPR/2014/7862
Diana Jussara do N. Malta, Larissa Cardoso C. Araújo, Aline S.G Carrazoni, Fernanda Virginia B. Mota, Sandra Cabral da Silva, Maria Andrea de S. Carmino, Maria do Carmo A. Lima, Ivan da Rocha Pitta & Teresinha Gonçalves da Silva·Journal of Pharmaceutical Research International·2014
Aims: The aim of this study was to investigate the anti-inflammatory, antiarthritic and antinociceptive effects of two thiazolidinedione derivatives: 3-(2-bromo-benzyl)-5-(4-methylsufonyl-benzylidene)-thiazolidine-2,4-dione (LPSF/GQ-125) and 3-(2,6-difluoro-benzyl)-5-(4-methylsuf...
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Research Article10.9734/BJPR/2014/8736
Aims: In much of Africa, Ghana inclusive, malaria has traditionally been diagnosed and treated presumptively: any patient with fever was presumed to have malaria and treated with antimalarial drugs. In this study, the retail pharmacies practitioners’ perspectives on the implement...
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Research Article10.9734/BJPR/2014/8910
Aims: The study aims to understand the wound healing potentials of a 50% aqueous ethanolic extract of Premna latifolia stem using excision wound model. Study Design: The wound healing potentials were simultaneously supported by observing the bacterial functional diversity of woun...
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Research Article10.9734/BJPR/2014/8787
Aim: To determine the phytochemical and antimicrobial properties of crude n-hexane and methanol extracts of Cola acuminata nuts against standard and clinical strains of pathogenic bacteria and fungi species implicated in various infections. Place and Duration of study: Department...
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Research Article10.9734/BJPR/2014/6960