Background: Angiogenesis refers to the formation of new blood vessels. This biological process lays an important role in embryonic development. Ceropegia pusilla (Asclepiadaceae) used in folk medicine system to treat various health problems. Present work deals with the analysis o...
Open access
Research Article10.9734/BJPR/2014/7481
Aims: To investigate the constituents and antimicrobial activity of essential oil from Vitex negundo seeds. Study Design: The essential oil of Vitex negundo seeds was prepared by hydrodistillation. GC/MS technique was used to determine the volatile constituents in the oil. A tota...
Open access
Research Article10.9734/BJPR/2014/7079
Aim: 1) To increase water solubility of indomethacin drug using mixed solvency approach. 2) To employ use of non toxic solubilizers for increasing solubility of a poorly water soluble drug. Study Design: Trial and error based experimental study. Place and Duration of Study: Schoo...
Open access
Research Article10.9734/BJPR/2014/4281
Aim: This study investigates the wound healing activity of ethanol leaf extract of Erythrina senegalensis using excision wound model on albino rats. Methodology: Several herbal extract formulations were prepared with Petroleum Jelly ointment base. Cicatrin® powder (neomycin-bacit...
Open access
Research Article10.9734/BJPR/2014/7260
Objectives: Buccal films consist mainly of polymer that has a good mucoadhesive profile and plasticizer. A lot of polymers and plasticizers can be used to configure the mucoadhesive films as hydroxyethyl cellulose and glycerin respectively. Material and Methods: Films prepared by...
Open access
Research Article10.9734/BJPR/2014/5399
Aims: The present study was conducted to confirm the angiogenic potential of honey using Chick Chorioallantoic Membrane (CAM), an in ovo model and to study its effect on Vascular Endothelial Growth Factor (VEGF) expression in the CAM tissue. Attempts were also made to identify th...
Open access
Research Article10.9734/BJPR/2014/6930
Aims: The objective of the current study was to formulate nystatin (Nyst) into nanostructured lipid carriers (NLCs) to enhance its antifungal activity. Place and Duration of Study: Department of pharmaceutical technology, national research centre, Egypt, between mars 2011 to apri...
Open access
Research Article10.9734/BJPR/2014/7055
Aims: The aims of the research were to synthesize, characterize some palmitoyl amino acids and their aromatic analogues and to screen the synthesized compounds for possible antibacterial activity Study Design: Synthesis, characterization and antibacterial screening of palmitoyl a...
Open access
Research Article10.9734/BJPR/2014/6063
Aims: Viola odorata is a medicinally important plant. It contains bioactive principle viz violin and probably methyl salicylic ester.The present study was designed to analyze the effect of different doses of this medicinal plant extract on meiotic and mitotic chromosomes of Vicia...
Open access
Research Article10.9734/BJPR/2014/5998
Aims: UV Spectrophotometric Method for the Simultaneous Determination of Desloratidine and Pseudoephedrine HCl in combined Dosage form. Study Design: A simple, rapid and specific UV spectroscopic method with good sensitivity was developed and validated for the simultaneous determ...
Open access
Research Article10.9734/BJPR/2014/5615
Aims: To investigate the effects of M. charantia on serum lipid profile, serum protein concentration and selected markers of cardiovascular damage in streptozotocin-induced diabetic Wistar rats. Study design: Forty healthy adult Wistar rats of both sexes were randomly assigned in...
Open access
Research Article10.9734/BJPR/2014/5320
Aims: To evaluate the In vitro cytotoxic effects of the hydro ethanolic extract (HEE) of the Delonix regia flowers against different cell lines. Methodology: The dried Delonix regia flowers are subjected to soxhlet extraction by using 70% ethanol. The dried extract was used to de...
Open access
Research Article10.9734/BJPR/2014/5746
Aims: Peripheral neuropathy (PN) is an identified risk of systemic antibacterial therapy with fluoroquinolones. The risk and its severity, including the development of Guillain-Barré syndrome (GBS) between individual agents is uncertain. This study examines the association betwee...
Open access
Research Article10.9734/BJPR/2014/6954
Aim: The study was aimed to evaluate Momordica charantia leaves extract for hepatoprotective effect against carbon tetrachloride (CCl4) induced hepatotoxicity in rats. Methodology: A total of twenty five male rats were randomly divided into five groups of five rats each. The extr...
Open access
Research Article10.9734/BJPR/2014/4885
Aims: The aim of the present work was to design and evaluate the Imatinib mesylate microspheres using natural and semi synthetic polymers for stomach specific drug delivery. Study Design: Design and Evaluation of Imatinib Mesylate loaded microspheres Place and Duration of the Stu...
Open access
Research Article10.9734/BJPR/2014/6444