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All published articles 7450

Prescription Pattern of Antibiotics among Physicians in a Secondary Health Facility in Abuja, Nigeria

Abu-Saeed Kamaldeen, Joseph Gbenga S. & Joseph Folake L. · Journal of Pharmaceutical Research International · 2013

Aim: This study was aimed at assessing the prescription pattern of antibiotics by physicians in Federal Staff Clinic, Abuja: A secondary health care facility in Nigeria. Study Design: It was a descriptive cross sectional study Place and Duration of Study: Federal Staff Clinic, Ab...

Open access Research Article 10.9734/BJPR/2013/4787

A Study on the Incidence of Infections and Infestations among the Malnourished Children of the Slum Area

Md. Sabir Hossain, Nayla Binte Iqbal, Md. Hafizur Rahman, Md. Tanvir Sarwar, Asad Ud- Daula, Md. Fuad Hossain & Md. Ibrahim Khalil · Journal of Pharmaceutical Research International · 2013

Aims: To make approaches to data collection and analysis for reviewing the impact of malnourishment upon the high incidence of infections and infestations among children in slum. Study Design: This prospective study was carried out among the total of 110 slum children and inciden...

Open access Research Article 10.9734/BJPR/2013/4812

Flavonol Glycosides from the Aerial Parts of Indigofera hirsuta and Anti-inflammatory Activity of n-butanol Fraction

L. S. Abbas, A. M. Musa, M. I. Abdullahi, M. G. Magaji, M. I. Sule & B. Bawa · Journal of Pharmaceutical Research International · 2013

Aims: The study aimed to phytochemically investigate the n-butanol soluble fraction of Indigofera hirsuta aerial parts and to evaluate the anti-inflammatory activity of the fraction using laboratory animal models. Study Design: Isolation and elucidation of the bioactive compounds...

Open access Research Article 10.9734/BJPR/2013/3609

Effect of Ethanolic Stem Bark Extract of Blighia unijugata (Sapindaceae) on Monosodium Glutamate-Induced Uterine Leiomyoma in Sprague-Dawley Rats

George Asumeng Koffuor, Kofi Annan, James Oppong Kyekyeku, Hope Korshie Fiadjoe & Ernest Enyan · Journal of Pharmaceutical Research International · 2013

Aims: To establish the presence of monosodium glutamate (MSG) as an ingredient of artificial food seasonings on the Ghanaian market, and to evaluate the anti-fibroid property of an ethanolic stem bark extract of Blighia unijugata on MSG-induced uterine leiomyoma in Sprague-Dawley...

Open access Research Article 10.9734/BJPR/2013/5402

Analgesic, Anti-Inflammatory and Antipyretic Effect of Mentha spicata (Spearmint)

Patwary Md, Hajjaj Yousuf, Nusrat Yousuf Noba, Mohammad Shohel, Rajib Bhattacherjee & Biplab Kumar Das · Journal of Pharmaceutical Research International · 2013

Aim: Mentha spicata (L.) is popularly used as herbal remedy for various ailments. But the scientific basis for its medicinal use especially in pain and inflammation remains unknown. Therefore, the present study was aimed to investigate the analgesic, anti-inflammatory and antipyr...

Open access Research Article 10.9734/BJPR/2013/4640

Formulation & Evaluation of Fast Dissolving Tablets of Amlodipine Besylate by Using Co-Processed Superdisintegrants

Jeevan T. Naikwade, Vikas V. Patil, Mayur H. Katkade, Vaibhav D. Thorat, Tahir Ansari & Chetan R. Vaidya · Journal of Pharmaceutical Research International · 2013

Aims: To formulate fast dissolving tablets of amlodipine besylate using co-processed superdisintigrant and evaluate the properties of fast dissolving tablets. Study Design: Formulation, evaluation of fast dissolving tablets of amlodipine besylate. Place and Duration of Study: Dep...

Open access Research Article 10.9734/BJPR/2013/4092

A Study Investigating the Absorption and Pharmacokinetics of a Newly Developed Paracetamol/Caffeine Formulation Containing Sodium Bicarbonate in Healthy Volunteers

Dongzhou J. Liu, Ashok Gupta & Mark J. Allison · Journal of Pharmaceutical Research International · 2013

Aims: To assess pharmacokinetic (PK) bioequivalence between a newly developed formulation, rapid-relese paracetamol plus sodium bicarbonate and caffeine (RAPC), containing 500 mg paracetamol + 65 mg caffeine + 325 mg sodium bicarbonate), and the currently marketed Panadol® Extra...

Open access Research Article 10.9734/BJPR/2013/4104

Stability of an Aspirin in the Aspirin+Curcumin Admixture at Different Storage Conditions

Hyun-Jin Kim, Min-A Kang, Yoo-Sin Park, Shin-Hee Kim & Ju-Seop Kang · Journal of Pharmaceutical Research International · 2013

Aims: The pure stability of aspirin in the aspirin (100 μg/mL) only and aspirin (100 μg/mL) +curcumin (600 μg/mL) admixture without any ingredient under two solvents (distilled water, DW and normal saline, NS), three storage temperatures (25ºC, 4ºC and -20ºC) and periods (1st, 3r...

Open access Research Article 10.9734/BJPR/2013/4083

Anticholinesterase, Antioxidant and Nitric Oxide Scavenging Activity of the Aqueous Extract of Some Medicinal Plants

Renu Agarwal, S. K. Gupta, Puneet Agarwal, S. Srivastava & Renad Alyayutdin · Journal of Pharmaceutical Research International · 2013

Aims: Enhancement of cholinergic activity and reduction of oxidative stress by scavenging free radicals such as nitric oxide are well recognized therapeutic approaches in several pathological conditions. We evaluated the anticholinesterase, antioxidant and nitric oxide scavenging...

Open access Research Article 10.9734/BJPR/2013/4833

Gastroprotective Activity of Methanol Leaves Extract of Barleria prionitis Linn. on Ethanol and Indomethacin Induced Ulcer in Rats

Manjusha ., Vipin Kumar & Surender Singh · Journal of Pharmaceutical Research International · 2013

Aims: Barleria prionitis L. (Family Acanthaceae) is a medicinal plant found road side in India and whole plant or its various parts like leaves, root, bark, stem and flowers are used traditionally for various treatments like toothache, inflammation, boils, glandular swellings and...

Open access Research Article 10.9734/BJPR/2013/3806

Bacterial Endophytes of the Medicinal Herb Hygrophila spinosa T. Anders and Their Antimicrobial Activity

Arundhati Pal & A. K. Paul · Journal of Pharmaceutical Research International · 2013

Aims: The ethnobotanical herb Hygrophila spinosa T. Anders (Acanthaceae) is native to India and used in traditional ayurvedic medicines for its pharmacologically important phytochemicals. This study aims to isolate and characterize the culturable bacterial endophytes of H. spinos...

Open access Research Article 10.9734/BJPR/2013/3698

Antimicrobial Activity of Stem Bark of Faidherbia albida

Wurochekke Abdullahi Usman, Mahmoud, Suleiman Jada & Zailani Hauwa Ahmed · Journal of Pharmaceutical Research International · 2013

This study was aimed at evaluating the antimicrobial activity of stem bark extract of Faidherbia albida on E. Coli, Salmonella typhi and Shigella sp. The study was conducted in laboratory of Biochemistry department of Modibbo Adama University of Technology, Yola, Adamawa, Nigeria...

Open access Research Article 10.9734/BJPR/2013/3209

Angiotensin-Converting Enzyme Inhibitory Activity of Passiflora edulis f. flavicarpa and Petroselinum crispum (Mill) Fuss

Rodrigo A. Restrepo, Nelsy Loango, Mónica V. Moncada & Patricia Landazuri · Journal of Pharmaceutical Research International · 2013

Aims: To determinate the angiotensin-converting enzyme inhibitory activity of several extracts from the species Passiflora edulis f. flavicarpa and Petroselinum crispum (Mill) Fuss. Study Design: Collection of plant material, extraction, preliminary phytochemical screening and ev...

Open access Research Article 10.9734/BJPR/2013/3517

Preparation and Evaluation of Solid Dispersions of Ibuprofen Using Glucosamine HCl as a Carrier

Abdul Wahab, Amjad Khan & Gul Majid Khan · Journal of Pharmaceutical Research International · 2013

Aims: The aim of this study was to enhance the solubility and dissolution rate of sparingly soluble drug ibuprofen using glucosamine HCL as a carrier by solid dispersion technique. Methodology: As Ibuprofen is sparingly water-soluble drug and has low bioavailability, so to enhanc...

Open access Research Article 10.9734/BJPR/2013/3479

In vitro Antioxidant, Cytotoxic and Antibacterial Screening of the leaves of Acridocarpous orientalis, Native to Sultanate of Oman

Ahlam Al-Abri, Hazaa Al-Maqbali, Afaf Weli, Sadri Said, Amzad Hossain & Md. Sohail Akhtar · Journal of Pharmaceutical Research International · 2013

Aims: To determine antioxidant, cytotoxic and antimicrobial activities of organic extracts from leaves of Acridocarpous orientalis (qafas) from Sultanate of Oman. Study Design: Brine shrimp test, DPPH assay and Disc diffusion method. Place and Duration of Study: School of Pharmac...

Open access Research Article 10.9734/BJPR/2013/4113