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All published articles 7450

Antimicrobial Resistance Evaluation of Organisms Isolated from Liquid Herbal Products Manufactured and Marketed in South Eastern Nigeria

N. T. Ujam, A. N. Oli, M. N. Ikegbunam, M. U. Adikwu & C. O. Esimone · Journal of Pharmaceutical Research International · 2013

Objective: To determine the susceptibility and resistance pattern of bacteria and fungi isolates obtained from herbal anti-infective liquid preparations manufactured and marketed in South-East Nigeria to conventional antibiotics. Study Design: Experimental Place and Duration of t...

Open access Research Article 10.9734/BJPR/2013/3554

Influence of Sodium CMC and HPMC on the Physical Characteristics of Ofloxacin Floating Matrix Tablets

Nagiat T. Hwisa, Babu Rao Chandu, Prakash Katakam & Varun Dasari · Journal of Pharmaceutical Research International · 2013

Aims: Sustained release floating drug delivery systems or gastro retentive drug delivery systems enables prolonged and continuous input of drug to the upper part of gastrointestinal tract and improves the bioavailability of medication. A new strategy is proposed for the developme...

Open access Research Article 10.9734/BJPR/2013/3949

Investigation of Consumer Attitudes, Intentions and Brand Loyal Behavior on the OTC Drugs in Bangladesh

Mohammad Shohel, Tasnuva Islam, Md. Mamun Al-Amin, Asiful Islam & M. Mahfuzur Rahman · Journal of Pharmaceutical Research International · 2013

Aims: To investigate the consumers’ attitudes and intentions to exhibit brand loyal behavior of Bangladeshi consumer on over the counter (OTC) drugs. Study Design: A cross- sectional survey. Place and Duration of Study: Consumers from the five major hospitals (Dhaka, Bangladesh)...

Open access Research Article 10.9734/BJPR/2013/3717

Effect of Aqueous Leaf Extract of Acalypha wilkesiana on Hematological Parameters in Male Wistar Albino Rats

Onome M. Iniaghe, Omoruyi Egharevba & Emmanuel B. Oyewo · Journal of Pharmaceutical Research International · 2013

Aims: The aim of this study is to evaluate the effect of aqueous leaf extract of Acalypha wilkesiana on hematological parameters in male wistar rats. Study Design: In_vivo. Place and Duration of Study: Department of Biochemistry, Faculty of Natural Sciences, Ambrose Alli Universi...

Open access Research Article 10.9734/BJPR/2013/2601

Simultaneous Determination of Hyoscine N- Butyl Bromide and Paracetamol by RP-TLC Spectrodensitometric Method

Nouruddin W. Ali, Mohammed Gamal & Mohammed Abdelkawy · Journal of Pharmaceutical Research International · 2013

Aims: A simple RP-TLC Spectrodensitometric method was developed for determination of Hyoscine N-Butyl Bromide (HBB) and Paracetamol (PAR) either in bulk powder or in their pharmaceutical preparation. Study Design: Validation study. Methodology: In this method, HBB and PAR were se...

Open access Research Article 10.9734/BJPR/2013/3522

Enhancing Quality of Life and Medication Adherence Through Patient Education and Counseling among HIV/AIDS Patients in Resource Limited Settings – Pre and Post Interventional Pilot Trial

E. Vigneshwaran, Y. Padmanabha Reddy & N. Devanna · Journal of Pharmaceutical Research International · 2013

Aims: The present study was undertaken to examine the effect of patient education and counseling by pharmacist on quality of life and medication adherence on patients living with HIV/AIDS in rural settings. Study Design: It is a single group (without control group) pre- post inte...

Open access Research Article 10.9734/BJPR/2013/2949

Regulated Effects of Capsicum frutescens Supplemented Diet (C.F.S.D) on Fasting Blood Glucose Level, Biochemical Parameters and Body Weight in Alloxan Induced Diabetic Wistar Rats

Ojieh E. Anthony, Adegor C. Ese & Ewhre O. Lawrence · Journal of Pharmaceutical Research International · 2013

Aim of the Study: This study investigates the effects of Capsicum frutescens supplemented diet (C.F.S.D) on fasting blood glucose level, biochemical parameters and body weight in alloxan induced diabetic Wistar rats. Experimental Design: 130 – 150g healthy forty male Wistar rats...

Open access Research Article 10.9734/BJPR/2013/3256

Stability Indicating Simultaneous Equation Method for Determination of Domperidone and (S)-Esomeprazole Magnesium in Capsule Dosage Form Using UV-Spectrophotometer

Sunil Singh, Jyoti Rai, Inamullah ., Nisha Choudhary, Hemendra Gautam, Surabhi Sharma, Ajit Kumar Yadav, Vipin Kumar Agrawal & Shashank Chaturvedi · Journal of Pharmaceutical Research International · 2013

Aims: Stability indicating simultaneous equation method for determination of Domperidone and Esomeprazole Magnesium in capsule dosage form using UV-Spectrophotometry. Study Design: A new simultaneous equation method was developed and validated for the determination of esomeprazol...

Open access Research Article 10.9734/BJPR/2013/3197

In Vitro and In Vivo Evaluation of Combined Time and pH- Dependent Oral Colonic Targeted Prednisolone Microspheres

Fahima M. Hashem, Dalia S. Shaker, Mohamed Nasr & Reem Ragaey · Journal of Pharmaceutical Research International · 2013

Aims: to enhance the anti-inflammatory effect as well as oral absorption of prednisolone (PR), through formulation of colonic targeted microspheres prepared from a blend of time and pH- dependent polymers and loaded with PR. Study Design: In Vitro and In Vivo Evaluation of Combin...

Open access Research Article 10.9734/BJPR/2013/3195

Studies on Phytochemistry of 100 Plants in Chennai, India

N. K. Udaya Prakash, S. Bhuvaneswari, A. Balamurugan, B. Radhika, R. Bhagya, N. Sripriya, L. Prameela, S. Sarojini, R. Vigneshwari, M. Chandran & S. Arokiyaraj · Journal of Pharmaceutical Research International · 2013

Aims: Knowledge on the plant phytochemistry provides a fundamental use of plants as a reservoir of chemical agents. Hence, the study on the presence of Phytochemicals in the aqueous extract of 100 different plant species belonging to 44 families collected from Chennai, India was...

Open access Research Article 10.9734/BJPR/2013/3201

Variation of Heavy Metal Content of Market Variants of Ayurvedic Formulation - Lack of Good Manufacturing Practices (GMP)

Vikas Gupta, Renu Bansal, Amit Lather & Parveen Bansal · Journal of Pharmaceutical Research International · 2013

Aim: The present study was conducted to estimate the heavy metal content in samples of Kutazghan Vati (a pill), from three different manufacturers to know about the quality control measures being followed by manufacturers for GMP. The study will also provide a platform for regula...

Open access Research Article 10.9734/BJPR/2013/3332

Development and Validation of New RP-UPLC Method for the Quantitative Analysis of Mycophenolate in Tablet Dosage Form

P. Raja Abhilash, K. Vasanth Kumar & V. Sateesh Kumar · Journal of Pharmaceutical Research International · 2013

Aim: To develop and validate a novel and rapid reverse phase ultra-performance liquid chromatographic (RP-UPLC) method for the estimation of mycophenolate in tablet formulations. Place and Duration of Study: Department of pharmaceutical analysis, S. R. College of Pharmacy anantha...

Open access Research Article 10.9734/BJPR/2013/2286

16α-Hydroxycholic Acid: In Vivo Microbial Transformation Product of Cholic Acid

Samira Al-Awadhi, Sosamma Oommen & Mohammad Afzal · Journal of Pharmaceutical Research International · 2013

Aims: This study describes the transformation of cholic acid to hydroxylated cholic acid metabolites that could not be easily synthesized. Study Design: The transformation was catalyzed by thermophilic Geobacillus stearothermophilus comb. nov., isolated from oil contaminated soil...

Open access Research Article 10.9734/BJPR/2013/3194

The Effect of Leaf Aqueous Extract of Brachystegia eurycoma Harms (Fabaceae) in Acute and Chronic Inflammatory Animal Models

I. Igbe & G. O. Inarumen · Journal of Pharmaceutical Research International · 2013

Aims: To investigate the effect of the leaf extract of Brachystegia eurycoma Harms (Leguminosae) in acute and chronic Inflammatory animal models. Study Design: Extraction and anti-inflammatory evaluation. Place and Duration of Study: Department of Pharmacology and Toxicology, Fac...

Open access Research Article 10.9734/BJPR/2013/2922