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All published articles 7450

Physicians' Knowledge and Perception of Antimicrobial Resistance: A Survey in Khartoum State Hospital Settings

Salah I. Kheder · Journal of Pharmaceutical Research International · 2013

Aims: To assess physicians' knowledge and perception regarding antimicrobial resistance and current antibiotic practices at the three main hospitals at Khartoum State-Sudan. Study Design: A cross- sectional survey. Place and Duration of Study: Physicians from the three main Khart...

Open access Research Article 10.9734/BJPR/2013/2117

Design and Characterization of Glyceryl Monostearate Solid Lipid Nanoparticles Prepared by High Shear Homogenization

A. R. Gardouh, Shadeed Gad, Hassan M. Ghonaim & Mamdouh M. Ghorab · Journal of Pharmaceutical Research International · 2013

Aims: The aim of this study was to explore the practicability of preparation of solid lipid nanoparticles of Glyceryl monostearate containing Dibenzoyl peroxide, Erythromycin base, and Triamcinolone acetonide as model drugs. The physicochemical properties of the prepared formulae...

Open access Research Article 10.9734/BJPR/2013/2770

Stability Indicating Methods for Determination of Nalbuphine- Hydrochloride

M. M. Fouad, S. A. Abdel Razeq, Z. A. Elsayed & L. A. Hussin · Journal of Pharmaceutical Research International · 2013

Three simple, sensitive and reproducible spectrometric methods for the selective determination of nalbuphine–HCl in presence of its oxidative degradate were investigated. The first method depended on the quantitative densitometric evaluation of thin layer chromatograms of the dru...

Open access Research Article 10.9734/BJPR/2013/2443

Ethanopharmacological and Phytochemical Aspects of Ocimum sanctum Linn- The Elixir of Life

Baby Joseph & Vrundha M. Nair · Journal of Pharmaceutical Research International · 2013

Ocimum sanctum Linn. (Tulsi), a sacred and traditional medicinal plant of India which belongs to the family Lamiaceae possesses innumerable health benefits and therefore regarded as the “Elixir of Life”. The entire plant body including its leaves, stem, root, inflorescence and se...

Open access Research Article 10.9734/BJPR/2013/2433

Formulation and In vitro Evaluation of Fluconazole Topical Gels

Aml Mekkawy, M. Fathy & Sohair El-Shanawany · Journal of Pharmaceutical Research International · 2013

Aims: Topical drug delivery of fluconazole, an antifungal drug, in gel form was formulated to avoid the side effect of the oral route. Study Design: In this study I prepare different formulation from different polymers and select the best formulation to undergo further antifungal...

Open access Research Article 10.9734/BJPR/2013/2775

Influence of Some Starch Mucilages on Compression Behaviour and Quality Parameters of Paracetamol Tablets

Musiliu O. Adedokun & Oludele A. Itiola · Journal of Pharmaceutical Research International · 2013

Aims: To evaluate the effect of mucilages of natural and pregelatinized forms of trifoliate yams, rice and official corn starch binders on a paracetamol tablet formulation. Methodology: Natural starches from two trifoliate yam varieties, and rice were isolated and pregelatinized....

Open access Research Article 10.9734/BJPR/2013/2120

Anti-Bacterial Effect of Different Fractionations of Acetic Acid Leaf Extract of Parinari curatellifolia

Eze, Henry Tochukwu & Wurochekke, Abdullahi Usman · Journal of Pharmaceutical Research International · 2013

The research was aimed at determining the anti-bacterial effect of different fractions of acetic acid leaf extract of Parinari curatellifolia. The research was conducted in laboratory unit of peace specialist hospital, Yola, Nigeria between May and November, 2011. Different solve...

Open access Research Article 10.9734/BJPR/2013/1772

Determination of Antioxidant Activity and Phytoconstituent Screening of Euphorbia heterophylla Linn

Muhammad Athar Abbasi, Hina Saleem, Aziz-ur-Rehman ., Tauheeda Riaz & Muhammad Ajaib · Journal of Pharmaceutical Research International · 2013

Aim: To carry out qualitative determination of phytochemicals and evaluate antioxidant potential of Euphorbia heterophylla Linn. Place and Duration of Study: Department of Chemistry, Government College University Lahore, Pakistan, between October, 2011 and February, 2012. Materia...

Open access Research Article 10.9734/BJPR/2013/1925

A Study of Some Effects of Aqueous Extract of Neem (Azadirachta Indica) Leaves on the Lead Acetate Induced Neurotoxicity in the Superficial Layers of Superior Colliculus of Adult Wistar Rats (Rattus norvegicus)

Fakunle Ponle Bamidele, Ajibade Adeshina John, Oyewo Emmanuel Bukoye & Adeyemi Oluwaseun Hannah · Journal of Pharmaceutical Research International · 2013

Aim: To investigate some neuroprotective effects of aqueous extract of Neem leaves against damaging actions of lead acetate induced neurotoxicity in the superficial layers of the superior colliculus of adult wistar rats. Study Design: Histological and Biochemical study. Place and...

Open access Research Article 10.9734/BJPR/2013/2344

Prasarani Sandhan, a Polyherbal Preparation, Shows Anti-nociceptive and Anti-inflammatory Activities

Mehdi Bin Samad, Ashraf-ul Kabir, Ninadh Malrina D’Costa & J. M. A. Hannan · Journal of Pharmaceutical Research International · 2013

Aims: Prasarani Sandhan (PRS) is an Ayurvedic formulation approved by the “National formulary of Ayurvedic Medicine 2011”, of Bangladesh. It is traditionally used in arthritic pain, lumbago and sciatia. Sparse scientific evidence is available to support the efficacy of this prepa...

Open access Research Article 10.9734/BJPR/2013/2310

Combined Oral Arginine and Monosodium Glutamate Exposure Induces Adverse Response on the Prostate Function and Testis Histology of Rats

Egbuonu A. C. Cemaluk, Ejikeme P. Madus, L. U. S. Ezeanyika & O. Obidoa · Journal of Pharmaceutical Research International · 2013

Aims: This study investigated the effect of exposure to arginine (ARG) and glutamate (GLU), or its variant, monosodium glutamate (MSG) on the prostate function and testis histology of rats. Study Design: Exposure to either ARG, GLU, monosodium glutamate (MSG), ARG plus GLU or ARG...

Open access Research Article 10.9734/BJPR/2013/2172

Design, Formulation and Evaluation of Piroxicam Capsules Prepared by Solid Dispersion Technique

Shady A. Swidan, Hassan M. Ghonaim, Mamdouh M. Ghorab & Ahmed M. Samy · Journal of Pharmaceutical Research International · 2013

Objective: To improve the dissolution of poorly soluble Piroxicam (PRXM) by solid dispersion technique using water soluble carriers with or without the addition of sodium lauryl sulphate (SLS) as surfactant. Methods and Materials: Solid dispersions of Piroxicam were prepared usin...

Open access Research Article 10.9734/BJPR/2013/2534

Antioxidant and Antibacterial Potential of Different Fractions from Roots of Eriosema chinense Vogel

Satyendra K. Prasad, Divya Jain, Manish Kumar & S. Hemalatha · Journal of Pharmaceutical Research International · 2013

Aim: The roots of the plant Eriosema chinense Vogel (Leguminosae-Papilionoideae) is taken in the form of vegetable and is traditionally used for the treatment of diarrhoea by the tribal people of Meghalaya, India. Therefore, the present study is an attempt to assess the antioxida...

Open access Research Article 10.9734/BJPR/2013/2661