Aims: Hypochlorous (HOCl) and hypobromous (HOBr) acids are among the most powerful oxidants produced by the innate immune cells. Albumin is the predominant protein in most body fluids and is considered the most important antioxidant of blood plasma. Study Design: Oxidation of bov...
Open access
Research Article10.9734/BJPR/2013/3066
Aims: The current study targets two main aims; 1st aim is the phytochemical investigation of the hexane extract of Chorisia crispiflora leaves. The 2nd aim is the evaluation of the in-vitro cytotoxic activity of the extract then examination of the molecular mechanisms underlying...
Open access
Research Article10.9734/BJPR/2013/2001
Aims: To formulate sustained release diclofenac potassium tablets based on solidified reverse micellar solution (SRMS) and to evaluate the in vitro and in vivo properties of the tablets. Study Design: Formulation, in vitro and in vivo evaluation of sustained release diclofenac po...
Open access
Research Article10.9734/BJPR/2013/1567
Aims: Pregnant women requiring medication represent a challenge to healthcare providers to avoid any teratogenic risk to fetus. The purpose of this study was to provide information about the drug use among pregnant women in a tertiary care hospital, Mumbai, India. Study Design: C...
Open access
Research Article10.9734/BJPR/2013/1943
Background: Conavir, an immunostimulant from aerial parts of Andrographis paniculata (AP) and Niprd-AM1, an antimalarial from roots of Nauclea latifolia (NL), are dry water extracts for capsulation. AP and NL have been in use in Asia and Africa for centuries. Purpose: The study a...
Open access
Research Article10.9734/BJPR/2013/1887
Aims: To study the current prescription pattern and to analyze the cost of the treatment Prescribed to RA patients referred to rheumatology OPD in KEM hospital. Study Design: Cross-sectional study. Place and Duration of Study: Department of Medicine and Department of Pharmacology...
Open access
Research Article10.9734/BJPR/2013/2229
Aims: To investigate the cytotoxic activity of rhoifolin against different cancer cell lines. Study Design: Isolation, identification and cytotoxic activity evaluation. Place and Duration of Study: Faculty of Pharmacy, Ain Shams University and Al-Azhar University, between October...
Open access
Research Article10.9734/BJPR/2013/1864
Background: Globally, in resistant malaria endemic zones, even the latest lines of MDTs (multi drug therapes) are yielding chaotic results. These include unacceptable side effects/contraindications, with poor prognosis in juveniles/adolescents. Juvenile stage is intensely humoral...
Open access
Research Article10.9734/BJPR/2013/2207
Blighia sapida is a medicinal plant used in Southern Nigeria for the treatment of some eye ailments and headache. The Centre for Scientific Research into Plant Medicine (CSRPM), Ghana, has used this plant for the treatment of diarrhea for over 20 years. Objective: This study was...
Open access
Research Article10.9734/BJPR/2012/1870
Aims: To evaluate the anti-inflammatory, antinociceptive and antiarthritis activities of methanolic extract of T. populnea flower (TPF) and root (TPR) extract; yet unreported. Study Design: Extraction and administration of bioactive extract. Place and Duration of Study: Departmen...
Open access
Research Article10.9734/BJPR/2012/1774
Aims: A simple and sensitive high performance liquid chromatographic (HPLC) method was developed for quantification of salbutamol in rat plasma. Terbutaline was used as an internal standard (IS). Study Design: Validation study. Methodology: The present method used solid phase ext...
Open access
Research Article10.9734/BJPR/2012/1279
Aims: To carry out the antistaphylococcal activity of n-butanol and aqueous sub-fractions of Alchornea cordifolia (Schumach. And Thonn.) Müll. Arg. leaf extract against multidrug resistant Staphylococcus aureus. Study Design: Characterization and antibiotic susceptibility determi...
Open access
Research Article10.9734/BJPR/2012/1727
Aim: To investigate the antiviral property of flavonoids from Cucumis metuliferus fruit pulp in chicken embryo fibroblast (CEF) cells and embryonated chicken eggs (ECE) induced with infectious bursal disease virus (IBDV). Study Design: Extraction and administration of bioactive e...
Open access
Research Article10.9734/BJPR/2012/1872
Aims: The crude ethanolic leaf extract of Bacopa monnieri (L) Penn. (family: Scrophulariaceae) was evaluated for its possible phytochemical nature (group determination of plant constituent) and selected pharmacological activities (analgesic, antidiarrhoeal and cytotoxic activity)...
Open access
Research Article10.9734/BJPR/2012/1951
Aim: To explore the ulceroprotective and antioxidant potential of Hyssopus officinalis in ethanol-induced gastric ulcer in rats. Study Design: Administration of plant extract and evaluation of antiulcer activity. Place and Duration of Study: Department of Pharmacology, Rayat Inst...
Open access
Research Article10.9734/BJPR/2012/1930