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All published articles 7450

A Review on Selected South Indian Regime of Tamil Nadu for the Seasonal Management of Communicable Diseases

M. Birundadevi, T. Sivapriya, T. Sindhuja & S. Mathukumar · Journal of Pharmaceutical Research International · 2022

Communicable diseases are infectious diseases that are caused by microorganisms such as bacteria, viruses, fungi, protozoa etc. Seasonal change in the infectious disease incidence is a common phenomenon in temperate and tropical climates such as India. The present covid-19 pandem...

Open access Research Article 10.9734/jpri/2022/v34i7B35467

A Review on Anthracycline Induced Cardiotoxicity- A Mechanism-based Approach

Sachin M. Hiradeve, Vaibhav P. Uplanchiwar, Namrata Mane, Gayatri Katole, Sanjana N. Gaikwad, Mayuri N. Deshmukh, Swati G. Gaikwad, Priya V. Nikam, Abhinav Bais, Vijendra Fulzele, Trupti S. Bobade & Mohd. Hashim Mansoori · Journal of Pharmaceutical Research International · 2022

Doxorubicin has become one of the most effective chemotherapeutic agents, but its use was complicated by the development of heart failure. Proposed mechanisms for its antitumor effects included intercalation into DNA that caused the prevention of micro molecule synthesis, DNA cro...

Open access Research Article 10.9734/jpri/2022/v34i7B35468

Observational Study Comparing the Safety and Efficacy of Igel Supraglottic Airway Device Insertion in Anesthetised Patients by Anesthesia Faculty versus Residents

Bhavini Shah, Dipanjali Mahanta, Krusha Shah & Jayalaxmi Mohan · Journal of Pharmaceutical Research International · 2022

Aims: Successful airway management is the first priority in a variety of emergency care and hospital scenarios. This study was an attempt to compare and find out how quickly a first-time resident can learn to insert an I-gel and secure the airway versus their trained counterparts...

Open access Research Article 10.9734/jpri/2022/v34i7B35466

Colposcopic Evaluation of Cervical Lesions with Swede Score and its Correlation with Histopathology

Chirag R. Sharma & N. S. Kshirsagar · Journal of Pharmaceutical Research International · 2022

Background & Objectives: Cervical cancer is the second most frequent cancer in India, with an estimated yearly diagnosis of 1, 23,907 women and 77,348 fatalities. The prevalence of cervical cancer remains high in poorer nations owing to budget constraints and a lack of access...

Open access Research Article 10.9734/jpri/2022/v34i7A35452

Synthesis, Characterization and Biological Evaluation N-[5-(1H-indol-3-yl)-1,3,4-thiadiazol-2-yl]methanimine Derivatives

Shruti Hirekurubar & Sanjeevkumar Giri · Journal of Pharmaceutical Research International · 2022

A new class of potentially biologically active new 1,3,4-thiadiazol derivatives have been prepared and reported in excellent yields. Its antioxidant properties were examined. It exhibited good activity, which had the highest in vitro anti oxidant properties against DPPH scavengin...

Open access Research Article 10.9734/jpri/2022/v34i7A36302

Comparison of Surface Roughness of Two Commercially Available Glass Ionomer Cements after Brushing Simulation with Herbal and Fluoridated Toothpaste - An In vitro Study

S. Obuli Ganesh Kishore, S. Jayalakshmi & S. Balaji Ganesh · Journal of Pharmaceutical Research International · 2022

Introduction:  Glass ionomer cement is a restorative material used in dentistry as a filling material and luting cement. Nowadays many consumers have started using natural toothpaste in order to avoid synthetic and artificial products. The aim of this study is to compare the surf...

Open access Research Article 10.9734/jpri/2022/v34i6B35435

Study of Factors Involved in Perforative Peritonitis and Its Significance to Mortality and Morbidity

Pulkit Bhalla, C. Z. Pardeshi & A. Y. Kshirsagar · Journal of Pharmaceutical Research International · 2022

Background: Peritonitis caused by gastrointestinal perforation is one of the most prevalent surgical emergencies worldwide. Early detection and treatment of Perforation Peritonitis may significantly minimize morbidity and death. The result is improved by surgical treatment and go...

Open access Research Article 10.9734/jpri/2022/v34i6B35436

Effect of Thermocycling on Colour Stability of Alkasite Restorative Material (Cention N) - An In Vitro Study

R. N. Arun Kishore, S. Balaji Ganesh & S. Jayalakshmi · Journal of Pharmaceutical Research International · 2022

Introduction: Cention N is an alkasite based dental restorative material, it is far less expensive unlike composite materials, it has fluoride releasing property and the strength of cention N is comparable to that of dental amalgam restorations. Colour stability is one of the maj...

Open access Research Article 10.9734/jpri/2022/v34i6B35437

Preliminary Investigation on the Prevalence and Antibiotics Susceptibility Pattern of Bacteria Associated with the Spoilage of Avocado Pear (Persea americana) Sold within Abakaliki, Ebonyi State, Nigeria

C. O. Okeh, P. C. Igwe, C. V. Uzoh, O. S. Chukwu, O. J. Owolabi, B. Ugwu, K. E. Aroh & I. Yusuf · Journal of Pharmaceutical Research International · 2022

The prevalence and antibiotic susceptibility pattern of bacteria associated with spoilage of avocado pear(Persea americana) were studied.A total of sixteen (16) avocado pear samples were collected from various markets in Abakaliki and these samples were bacteriologically examined...

Open access Research Article 10.9734/jpri/2022/v34i7A35438

Transdermal Drug Delivery System: A Novel Alternative for Drug Delivery

Bharat Lal & Manoj Gadewar · Journal of Pharmaceutical Research International · 2022

Orally administered pharmaceuticals now account for 74% of all prescriptions, however studies have shown that oral medications are often less  effective due to first pass metabolism and not stable drug blood level etc. Transdermal drug delivery system (TDDS) was developed to enha...

Open access Research Article 10.9734/jpri/2022/v34i7A35448

Anterior Cruciate Ligament Injury: A Review

Ankit Mittal, Siddharth Jain, Ratnakar Ambade & Suhas Landge · Journal of Pharmaceutical Research International · 2022

Anterior Cruciate Ligament (ACL) injury is now the most debatable ligamentous injury. It has been widely researched over the last 25 years all over the world. Over the last few decades, ACL repair surgery has advanced significantly. Anterior cruciate ligament reconstruction (ACLR...

Open access Research Article 10.9734/jpri/2022/v34i7A35449

Formulation of Silver Nanoparticles using Gymnema sylvestre Leaf Extract and In-vitro Anti-diabetic Activity

Ajinkya B. Chavan, Swapnil Goyal & Ansar M. Patel · Journal of Pharmaceutical Research International · 2022

Aim: Formulation of Silver Nanoparticles Using Gymnema sylvestre Leaf Extract and In-Vitro Anti-diabetic Activity. Place and Duration of the Study: The present work has been carried out between April-2021 to July-2021 and at Mandasur University Mandsaur, Madhya Pradesh-458001. Me...

Open access Research Article 10.9734/jpri/2022/v34i7A35450

Multisystem Inflammatory Syndrome in Children- A Case Study from a Tertiary Care Centre in Maharashtra, India

V. Y. Kshirsagar & Nagza Kakkar · Journal of Pharmaceutical Research International · 2022

Background: A multisystem inflammatory syndrome in children (MIS-C) is associated with coronavirus disease 2019. Understanding the epidemiology and clinical course of multisystem inflammatory syndrome in children (MIS-C) and its association with Covid-19 is important, given the c...

Open access Research Article 10.9734/jpri/2022/v34i7A35451

Comparison of the Effect of Olanzapine, Haloperidol and Quetiapine on the Resolution of Individual Delirium Symptoms in ICU Patients: A Double-blind, Clinical Trial Study

Mohammad Eslami, Seyed Mohammad Jamalian, Mahdi Nikoohemmat, Alireza Kamali & Behnam Mahmoodiyeh · Journal of Pharmaceutical Research International · 2022

Introduction: Considering that haloperidol is a first-generation antipsychotic drug known as the primary treatment for delirium, it causes extrapyramidal side effects, and olanzapine and quetiapine are second-generation antipsychotic drugs without extrapyramidal side effects. In...

Open access Research Article 10.9734/jpri/2022/v34i6B35432