Ajirioghene E. Akpotu

Attenuating Effect of Fraction of Dryopteris dilatata on Alloxan-induced Oxidative Stress and Hepato-nephro Injury in Wistar Rat Models

Ajirioghene E. Akpotu, Samuel I. Ghasi, Ehoro O. Odu, Victoria O. Chukwu, Omoighele F. Akhigbe, Micheal A. Amadi, Oghenefejiro F. Ovowa & Destiny E. Omorhienrhien · European Journal of Medicinal Plants · 2025

Aims: Prolonged hyperglycemia leads to diabetes mellitus, causes serious complications which is a major concern affecting global economy.  Dryopteris dilatata (Dd) leaf contains phytochemicals with capacity to treat metabolic disorders.  The present study was carried out to evalu...

Open access Research Article 10.9734/ejmp/2025/v36i41285

Reducing Sugar, Alkaloid and Tannin from Dryopteris dilatata Fractions Modulates Diabetogenic and Oxidative Stress Activity on Alloxan Induced Diabetic Rats

Ajirioghene E. Akpotu, Samuel I. Ghasi, Amalachukwu O. Ike, Omoighele F. Akhigbe, Micheal A. Amadi, Daniel O. J. Ajah, Funso-Babarimisa, Funso, Victoria O. Chukwu & Martins U. Ukiwa · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2024

Active components in medicinal plants possess therapeutic indications in disease states. Aim: The present investigation evaluated the activity of fraction from Dryopteris dilatata leaves modulating diabetogenic and oxidative stress activity in alloxan-induced diabetic Rats. Metho...

Open access Research Article 10.9734/ajrimps/2024/v13i3259

Free Radical Scavenging Activity and Phytochemical Investigation of Ethanol Leaf Extract of Dryopteris dilatata

Ajirioghene E. Akpotu, Samuel I. Ghasi, Doris N. Ajibo, Amalachukwu O. Ike, Amenotie Joy Akhator, Joseph Igbo Enya & Ijeoma Onyeleonu · Journal of Complementary and Alternative Medical Research · 2023

Bioactive constituents are the active ingredients of herbal product such as Dryopteris dilataa that possess therapeutic efficacies in the treatment and management of several diseases. Thus, we evaluated different concentration of the free radical scavenging activity and phytochem...

Open access Research Article 10.9734/jocamr/2023/v22i2455

Methanol Extract of Dryopteris dilatata Alleviates streptozotocin-induced Hyperglycaemia and Liver Injury in Male Wistar Rats in Type 2 Diabetes Mellitus

Ajirioghene E. Akpotu, Gospel Nwikue, A. I. L. Bassey, Silver D. Isosiya, Ajibo Doris & Ckikere A. Anusiem · Journal of Complementary and Alternative Medical Research · 2022

Dysfunctional pancreatic beta cell and impaired glucose metabolism in the liver has been implicated in streptozotocin (STZ)-type 2 diabetes mellitus and this has been linked with increased oxidative stress. Whether methanol extract of Dryopteris dilatata (MEDd), a flavonoid-rich...

Open access Research Article 10.9734/jocamr/2022/v19i3391

Information and Communication Technology Utilization in Post Basic Nursing Programme in the University of Port Harcourt Teaching Hospital

Oghenereke Odu Ehoro, Evidence Ngozi Otobo, Ajirioghene E. Akpotu & NDIDI ALERUCHI ONWUKW · Asian Journal of Research in Nursing and Health · 2025

This study investigates the use of Information and Communication Technology (ICT) in the Post Basic Nursing Programme at the University of Port Harcourt Teaching Hospital (UPTH). The objectives were to assess the extent of ICT usage among students and lecturers and identify key f...

Open access Research Article 10.9734/ajrnh/2025/v8i1218

Anti-Inflammatory Activity of Ethanol Leaf Extract of Arthropteris Orientalis in Wistar Albino Rat

Akhigbe Faith Omoighele, Ckikere A. Anusiem, Samuel I. Ghasi, Ajirioghene E. Akpotu, Chidi E. Ezerioha & Funso-Babarimisa, Funso · Journal of Complementary and Alternative Medical Research · 2023

The study investigated the anti-inflammatory activity of ethanol leaf extract of Arthropteris orientalis in wistar albino rat. The plant extract was obtained with the procedure as described by Khalifa et al. [1] and both acute and chronic anti-inflammatory properties was assessed...

Open access Research Article 10.9734/jocamr/2023/v24i3502