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Organics

Published by MDPI AG · ISSN (electronic) 2673-401X

Organic chemistry
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212

Articles indexed

36

2026 articles

211

Open access

2,519

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Articles (212)

Synthesis of Bipyridine Ether-Type Bifunctional Precursors

Bálint Jávor, Antal Agárdi, Péter Kisfaludi, Barnabás Frigyes, Márton Temesvári, Panna Vezse, Tünde Tóth, Péter Huszthy & Ádám Golcs · Organics · 2025

Bipyridine ethers are commonly occurring structural motifs in supramolecular chemistry. The herein reported efforts aim to extend the synthetic platform of bipyridino-precursors with new bifunctional intermediates and to improve some previously reported synthetic strategies for s...

Open access Research Article 10.3390/org6020018

Small Deviations in Geometries Affect Detonation Velocities and Pressures of Nitroaromatic Molecules

Danijela S. Kretić, Marija I. Maslarević & Dušan Ž. Veljković · Organics · 2025

Understanding the factors that affect the detonation performance of high-energy molecules (HEMs) is crucial for the design of novel explosives and fuels with desirable characteristics. While molecular factors, such as the presence of specific functional groups that give organic m...

Open access Research Article 10.3390/org6020017

An Overview of Quinolones as Potential Drugs: Synthesis, Reactivity and Biological Activities

Ayoub El-mrabet, Amal Haoudi, Youssef Kandri-Rodi & Ahmed Mazzah · Organics · 2025

Quinolones represent one of the largest classes of synthetic antibiotics used in both human and veterinary medicine. Since the discovery of nalidixic acid, a substantial body of research has been carried out on quinolones, resulting in the synthesis of several quinolone derivativ...

Open access Research Article 10.3390/org6020016

Synthesis of Indole-Based Derivatives Containing Ammonium Salts, Diamines and Aminoureas for Organocatalysis

Marcello Casertano, Brian G. Kelly, Malachi W. Gillick-Healy, Paolo Grieco & Mauro F. A. Adamo · Organics · 2025

Indole heterocycles have an established reactivity, and these compounds are H-bond donors via a peculiar non-basic NH. However, the indole core has been scarcely employed in organocatalysis, with only a few examples relevant to electrophilic halogenation reported. To expand the r...

Open access Research Article 10.3390/org6020015

Optimized Synthesis of Dinitrochalcones via Ultrasonic Bath in a Cyclohexane–Methanol Solvent System

Alam Yair Hidalgo, Quirino Torres-Sauret, Carlos Ernesto Lobato-García, Erika Madeleyne Ramos-Rivera, Luis Fernando Roa de la Fuente, Abraham Gómez-Rivera, Miguel Ángel Vilchis-Reyes, Erika Alarcón-Matus, Oswaldo Hernández-Abreu & Nancy Romero-Ceronio · Organics · 2025

This study describes the efficient synthesis of five dinitrochalcones (DNCHs) using an ultrasonic bath as an unconventional method to improve reaction yields and reduce reaction times. The Claisen–Schmidt condensation of nitroacetophenones and nitrobenzaldehydes was carried out i...

Open access Research Article 10.3390/org6020014

Luminescence of the Conjugate Bases of [2-(2-Hydroxyphenyl)phenyl]phosphinic Acid and Single-Crystal X-Ray Structure Determination of Sodium [2-(2-Hydroxyphenyl)phenyl]phosphinate

Valeria Gagliardi, Jesús Castro, Valentina Beghetto, María Expósito & Marco Bortoluzzi · Organics · 2025

The commercial flame-retardant 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide (DOPO) was almost quantitatively converted in sodium [2-(2-hydroxyphenyl)phenyl]phosphinate Na[OH-Ph-Ph-PHO2] and disodium 2-(2-phosphinatophenyl)benzen-1-olate Na2[O-Ph-Ph-PHO2] under mild reaction...

Open access Research Article 10.3390/org6010010

Synthesis and Biological Evaluation of Salicylaldehyde-Derived Secondary Amines: Antioxidant, Anti-Inflammatory, and Insecticidal Activities with DFT Insights

Chamseddine Derabli, Noureddine Rahim, Roumaissa Djaba, Sarra Aouidi, Chawki Bensouici, Stephanie Hesse & Houssem Boulebd · Organics · 2025

Six secondary amine derivatives derived from salicylaldehyde (SA) were successfully synthesized in good to excellent yields and evaluated for their biological activities. The synthesized compounds exhibited remarkable antioxidant properties, as determined by ABTS and phenanthroli...

Open access Research Article 10.3390/org6010011