Anti-diabetic, Anti-cancer Potential and Anti HIV of Bitter Gourd (Momordica charantia) Extract: A Mini Review
Asian Plant Research Journal · pp. 66–77 · Published 17 Jul 2024
10.9734/aprj/2024/v12i4263Abstract
Aims: To review the antidiabetic properties, pharmacological characteristics, and phytochemical research on Momordica Ccharantia (bitter gourd) and assess its potential as a therapeutic agent for diabetes and cancer prevention. Study Design: Review of existing literature and research studies, including pre-clinical trials and animal and in vitro studies. Methodology: Analysis of traditional uses, pharmacological data, and phytochemical research on M. Charantia. Evaluation of anti-diabetic and anti-HIV properties based on available studies. Results: • Charantia has shown anti-diabetic and hypoglycemic effects in pre-clinical studies. • Limited and unreliable clinical data due to poor research design and inadequate statistical power. • Recent studies indicate potential anti-tumor, anti-diabetic, and anti-HIV properties. • Plant extract components have demonstrated effectiveness in cancer prevention through immune function enhancement, induction of cell death, and inhibition of cancer-related processes. Conclusion: M. Charantia holds promise as a therapeutic agent for diabetes management and cancer prevention. However, there is a need for better-designed clinical trials to confirm its efficacy and establish reliable clinical evidence.
References (20)
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Cited by 6
Rizwan Ahmad, A. Alqathama · Frontiers in Nutrition · 2026
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Adfar Reyaz, Syed Sanober Qadri, Darakhshan Javaid · Phytomedicine Plus · 2025
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