Study of the Role of Protein S in Patients with Coronavirus Disease 2019

Abstract

Background: A novel coronavirus disease 2019 (COVID 19) was found for the first time in late 2019 in Wuhan, China, and swiftly transmitted throughout the globe, resulting in a pandemic. The virus was determined as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and       the World Health Organization (WHO) recognized the condition as coronavirus disease 2019 (COVID-19). Aim of the Work: To assess the role of protein S in COVID 19 cases. Patients and Methods: Study area setting: The research was applied in Clinical Pathology Department, Faculty of Medicine, Tanta University.  Group I:  15 normal subjects with matched age and sex to patient group as a control group and II: 40 patients diagnosed with PCR as COVID -19 positive. Which include 25% of patients had severe disease, 55% had moderate severity, and 20% had mild disease. Results: COVID-19 infection has a significant influence on the blood coagulation cascade, which might result in the presentation of serious signs and elevated mortalities.