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All published articles 7450

Nanomedicine in Treatment of Typhoid Fever: A Review

Swati Pund, Nitin Kharat, Shaikh Sohel Shaikh Khalil, Shoebuddin Zaheeroddin Shaikh, Chetan Pulate & Harshal Tare · Journal of Pharmaceutical Research International · 2022

For effective management of typhoid, diagnosis of the disease must be done with speed and accuracy. Laboratory diagnosis of typhoid fever requires isolation and identification of Salmonella enterica serotype Typhi. In many areas where the disease is endemic, laboratory capability...

Open access Research Article 10.9734/jpri/2022/v34i24A35931

Evaluation of Anti Estrogenic Activity and Anti-Osteoporotic Activity of Extracted Quercetin from Bambusa arundinacea Leaves on Ovariectomized Rats

Akankasha Awasthi, Divya Juyal, Mamta F. Singh & Saurabh Sharma · Journal of Pharmaceutical Research International · 2022

Phytoestrogens has now become a emerging era of interest for the researchers. The mimicking effects of phytoestrogens had lead to its wide use in reproductive system. In this study it was aimed to study the estrogenic activity and anti-osteoporotic activity of isolated quercetin...

Open access Research Article 10.9734/jpri/2022/v34i24A35930

Antimicrobial Therapy: An Important Risk for Acquired Aplastic Anemia

Muhammad Asif Syed, Nasreen Qazi, Shah Nawaz Jamali, Ashique Ali Arain, Sadat Memon & Ganesh Kumar · Journal of Pharmaceutical Research International · 2022

Background: Aplastic anemia although a rare hematological disorder but it is associated with poor prognosis and high mortality. It is a matter of greater public health concern for the Asian population with prevalence 3 times greater than other part of the globe. Exposures of spec...

Open access Research Article 10.9734/jpri/2022/v34i24A35933

RP-HPLC Method Development and Validation for the Estimation of Chlordiazepoxide in Novel Excipient Containing Formulations

Dada Kodalkar, Ajit Kulkarni & Birendra Shrivastav · Journal of Pharmaceutical Research International · 2022

An effort has been made to establish a simple and exact reverse-phase HPLC technique for the analysis of Chlordiazepoxide in bulk medication and formulations. A Phenomenex Luna C18 stationary phase (250 4.6 mm, 5) and dipotassium hydrogen phosphate anhydrous buffer (pH 6.8) and a...

Open access Research Article 10.9734/jpri/2022/v34i24A35934

Prevalence of Acute Stent Thrombosis after Primary PCI in STEMI Patients

Sanaullah Shaikh, Zuhaib Uddin, Zeeshan Shaikh, Naveed Ahmed Shaikh, Javed Khurshed Shaikh, Ghulam Jaffar Shah, Syed Taimour Hussain & Ayesha Samad · Journal of Pharmaceutical Research International · 2022

Background: In-hospital mortality data of patients who have been experiencing ST (stent thrombosis) shows 7.9% statistics for acute stent thrombosis (AST) within 24 hours of PCI, Sub-Acute Stent Thrombosis (SAST) occurs during 30 days of Percutaneous Coronary Intervention (PCI),...

Open access Research Article 10.9734/jpri/2022/v34i24B35935

Topical Lidocaine Medicated Plaster 5% and Pregabalin for the Treatment of Post-Herpetic Neuralgia: A Systematic Review and Meta-Analysis

Hassan A. Moria · Journal of Pharmaceutical Research International · 2022

Background and objectives: Post-herpetic neuralgia is common severe pain that leads to poor quality of life. Various topical and systemic drugs were in use including topical lidocaine medicated plaster 5% (05% LMP. This is the first meta-analysis to compare 5% lidocaine medicated...

Open access Research Article 10.9734/jpri/2022/v34i24B35937

Revascularization Using Lesion Sterilization and Tissue Repair: A Case Report

M. Robert Justin, Snehal Ughade, Aditi Sarda, Pankaj Chavhan, Nutan Gutte & Pratima Kolekar · Journal of Pharmaceutical Research International · 2022

Clinicians encounter a variety of scenarios in which a permanent tooth has been damaged by trauma, followed by peri-radicular alteration, and is beyond the scope of typical endodontic operations to save. Because of the limited root length, it is difficult to keep a permanent toot...

Open access Research Article 10.9734/jpri/2022/v34i23B35925

Stress Induced Menstrual Cycle Irregularities AMIDST the Pandemic

Shazia Rani, Saira Dars, Marvee Soho, Naheed Akhtar, Khalil Kazi & Aatir H. Rajput · Journal of Pharmaceutical Research International · 2022

Background: The global pandemic of the coronavirus disease 2019 (COVID-19) has yielded a variety of stressors (psychosocial) for the population, particularly women. The elevated stress may not only affect the wellbeing and health (physical and mental) of women, but also the repro...

Open access Research Article 10.9734/jpri/2022/v34i23B35924

HPLC Method Development for the Estimation of Empagliflozin in Bulk and Pharmaceutical Formulation

Asmita V. Gaikwad & Preeti Khulbe · Journal of Pharmaceutical Research International · 2022

An efficient and simple HPLC method has been developed and validated for the determination of Empagliflozin in marketed formulations. The mobile phase used for the chromatographic runs consisted of Water:ACN (55:45 v/v). The separation was achieved on a Symmetry, Waters C-18, 100...

Open access Research Article 10.9734/jpri/2022/v34i23B35926

The Effects of Sociodemographic Factors on the use of Supplementary Vitamins and the Follow Hygiene Rules in the COVID-19 Pandemic in TRNC

Şevval Çağdaş & Hasan Zafer Acar · Journal of Pharmaceutical Research International · 2022

Background: In order to reduce the spread of the disease and death rates in the Covid-19 Pandemic, it is important to use supplementary vitamins that increase body resistance, such as vitamin D and vitamin C, and to following some hygiene rules. In the Covid-19 pandemic, some soc...

Open access Research Article 10.9734/jpri/2022/v34i23B35927

Post Vaccination Side Effects of Different Available Vaccines among People of Karachi, Pakistan: A Cross Sectional Study

Hira Akhtar, Saira Shahnaz, Muhammad Ali, Quratulain Legari, Maha Raja Dahar, Salman Ashfaq Ahmed & Khawar Khalid · Journal of Pharmaceutical Research International · 2022

Background: For the suppression of covid-19 virus development of vaccines are one of the foremost step but this rapid development enlarge the probability of side effects. In this study a questionnaire based survey conducted to evaluate post covid vaccination short term side effec...

Open access Research Article 10.9734/jpri/2022/v34i23B35875

Development and Evaluation of Ceftazidime Loaded Microemulsion for Parenteral Drug Delivery System

Bhushan Hatwar, Ashish Jain & Akhlesh Kumar Singhai · Journal of Pharmaceutical Research International · 2022

The goal of this study was to develop a parenteral microemulsion formulation of Ceftazidime antibiotics. The ceftazidime sparingly soluble in organic solvent like ethanol, DMSO, and dimethyl formamide were determined. For biological experiment, organic solvent- free aqueous solut...

Open access Research Article 10.9734/jpri/2022/v34i23A35867

Intestinal Obstruction Etiology, Diagnosis and Management

Haider Osman Ibn Idris Elmisbah, Abdulazez Aweed Mehdy Alonezy, Sulaiman Turki Arfaj Alanazi & Sultan Nawi Arfaj Alanazi · Journal of Pharmaceutical Research International · 2022

Bowel obstruction is a leading cause of illness and mortality in the United States. Mechanical intrinsic luminal blockage or extrinsic compression are the causes of bowel obstruction. A full blood count and a metabolic panel must be performed on patients with suspected blockage i...

Open access Research Article 10.9734/jpri/2022/v34i23A35873

Determination of Cytotoxic Effects of Silver Diamine Fluoride/ Potassium Iodide Agent on Human Peripheral Lymphocytes

Semanur Özüdoğru, Giray Buğra Akbaba & Fikret Özgür Coşkun · Journal of Pharmaceutical Research International · 2022

Aim: To investigate cytotoxicity effect of different concentrations of Silver Diamine Fluoride/Potassium Iodide agent on human peripheral blood lymphocytes. Materials and Methods: The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was used to determine t...

Open access Research Article 10.9734/jpri/2022/v34i23A35870