Diabetes mellitus remains a major global health challenge, necessitating the exploration of safer and more effective therapeutic agents. This study investigated the inhibitory effects of Cucurbita maxima on α-amylase activity and its impact on glycemic control in alloxan-induced...
Open access
Research Article10.9734/jocamr/2026/v27i5756
Background: Kidney-liver crosstalk contributes to increased mortality from acute kidney injury. Brachystegia eurycoma leaves are used in herbal remedies to promote diuresis, treat renal stones, and address kidney issues. Aim: This study evaluated the ability of B. eurycoma to ame...
Open access
Research Article10.9734/jocamr/2026/v27i5755
Biomarkers and personalized medicine have significantly transformed modern healthcare by enabling precise diagnosis, disease prediction, targeted therapy, and individualized patient management. Biomarkers are measurable biological indicators that reflect physiological, pathologic...
Open access
Research Article10.9734/jocamr/2026/v27i5754
Background: Ethnogynaecological knowledge in Akwa Ibom State reflects a deeply rooted reliance on medicinal plants for women’s reproductive healthcare, yet this indigenous medical heritage remains underdocumented and increasingly vulnerable to cultural erosion. Aims: To document...
Open access
Research Article10.9734/jocamr/2026/v27i5753
Background: Conversational artificial intelligence (AI) tools have become increasingly integrated into the daily lives of young adults for educational, emotional, and productivity-related purposes. Despite growing reliance on these technologies, their psychological impact on yout...
Open access
Research Article10.9734/jocamr/2026/v27i5752
Background: Diarrhea during pregnancy poses significant maternal and fetal risks, particularly when associated with dehydration and electrolyte imbalance. Aim: This study investigates the effects of loperamide on castor oil-induced diarrhea in pregnant Wistar rats and evaluates i...
Open access
Research Article10.9734/jocamr/2026/v27i4751
Diabetes mellitus is a major chronic metabolic disorder associated with persistent hyperglycemia and multiple long-term complications, including cardiovascular, renal, neurological, and hepatic abnormalities. Although conventional antidiabetic medications remain the primary treat...
Open access
Research Article10.9734/jocamr/2026/v27i4749
Hypertension is a major global health challenge and a leading risk factor for cardiovascular diseases. It is commonly associated with activation of the renin–angiotensin system (RAS), oxidative stress, and metabolic disturbances, which contribute to the progression of cardiovascu...
Open access
Research Article10.9734/jocamr/2026/v27i4750
The increasing consumption of herbal formulations necessitates systematic safety evaluation, particularly for widely marketed polyherbal beverages such as Jigsimur, reportedly formulated from Aloe ferox sap. This study investigated the acute and subacute toxicity profile of Jigsi...
Open access
Research Article10.9734/jocamr/2026/v27i4748
Rheumatoid arthritis (RA) is a chronic, systemic autoimmune inflammatory disease characterised by persistent synovitis, progressive joint destruction, and extra-articular manifestations, affecting approximately 0.5–1% of the global population. Whilst conventional pharmacological...
Open access
Research Article10.9734/jocamr/2026/v27i4747
Background: Rheumatoid Arthritis (RA) is a chronic systemic autoimmune disorder characterised by persistent synovial inflammation of immune system overactivation and oxidative stress. Objectives: This study aimed to assess serum levels of procalcitonin and selected oxidative stre...
Open access
Research Article10.9734/jocamr/2026/v27i3746
Background: Pyracantha crenulata (D. Don.) M. Roem. is an evergreen shrub also called as Himalayan firethorn, belongs to family Rosaceae inherent in the Himalayan areas of India, China and Nepal. Various parts of the plant have long been used in traditional medicine for the treat...
Open access
Research Article10.9734/jocamr/2026/v27i3744
Background: Bisphenol A (BPA) is a widely used industrial chemical with endocrine-disrupting properties, posing significant risks to human health, particularly through its neurotoxic and oxidative stress–inducing effects. Antioxidant-based interventions, such as D-ribose L-cystei...
Open access
Research Article10.9734/jocamr/2026/v27i3745
Introduction: Natural products, like plant extracts either as pure compounds or as standardized extracts, provide unlimited opportunities for new drug discoveries because of their unmatched availability of chemical diversity. Scientific evidence from clinical trials to authentica...
Open access
Research Article10.9734/jocamr/2026/v27i3742
Background: The effect of configuration of implant superstructure, namely screw-retained zirconia crowns versus cement retained metal-ceramic crowns on local inflammatory biomarker profiles is not yet fully characterized although emerging evidence demonstrates the effects of supe...
Open access
Research Article10.9734/jocamr/2026/v27i3743