Aims: A simple TLC Spectrodensitometric method was developed for analysis of Orphenadrine Citrate (OR), Caffeine (CAF) and Aspirin (ASP) either in pure form or in their pharmaceutical preparations. Study Design: Validation study. Methodology: In this method, The three drugs were...
Open access
Research Article10.9734/bjpr/2016/31194
Purpose: To develop a highly selective, reproducible & precise rugged bio analytical method for estimation of Bortezomib (BTZ), “A Protease Inhibitor” in human plasma by validating the developed method in accordance to US-FDA guidelines. Methodology Envisaged: BTZ D3 was used as...
Open access
Research Article10.9734/bjpr/2016/30565
The Phytochemical and antibacterial activities of Calotropis procera Leaf Organic Fractions were tested against vancomycin and methicliin resistant bacteria isolated from wound patients in Ondo State Specialist Hospital. The bacterial isolates are; Staphylococcus aureus, Escheric...
Open access
Research Article10.9734/bjpr/2016/30974
Seed oils of watermelon, unripe and ripe pawpaw were extracted and analyzed for their fatty acid composition using GC/EIMS, phenolic content and antioxidant potential using free radical scavenging effect on 2, 2-diphenyl-2-picrylhydrazyl (DPPH) radical. Watermelon seed oil has ei...
Open access
Research Article10.9734/bjpr/2016/27974
Objective: Lubricants are additives which reduce friction and so essential components of drug formulation. This piece of work was initiated to evaluate coconut oil as a co-processed lubricant in the formulation and compression of paracetamol tablets in comparison with magnesium s...
Open access
Research Article10.9734/bjpr/2016/31379
Ocimum sanctum (L) is a well-known herbal plant used for the treatment of bronchitis, malaria, diarrhea, dysentery, skin disease, arthritis, eye diseases and insect bites. It is proposed to have anticancer, antidiabetic, antifungal, antimicrobial, cardio protective, analgesic and...
Open access
Research Article10.9734/bjpr/2016/31445
Fipronil (FPN) is a wide-spectrum insecticide and has been extensively used in agriculture since 1990s. The current study was deliberated to inspect the retrograde effects of exposure to the FPN on the hepatic tissues of male rats at concentration 10 mg/L in drinking water for 30...
Open access
Research Article10.9734/bjpr/2016/23660
Aim: The aim of this research was to optimize the reaction conditions for the production of silver nanoparticles sufficiently bioactive for incorporation into pharmaceutical gels. Methods: Silver nanoparticles were prepared by silver nitrate-sodium borohydride reduction method un...
Open access
Research Article10.9734/bjpr/2016/30324
Aristide Kognou, Rajesh Pawar, Rosalie Ngane, Pradeep Pateriya, Prem Pal, Alembert Tchinda, Gabriel Agbor, Rebecca Etame, Raymond Mouokeu, Albert Mouelle & Cecile Gueiffier·British Journal of Pharmaceutical Research·2016
Aims: This study was designed to elucidate the antioxidant, analgesic and antipyretic activities of the ethanol extract of the stem bark of Dichaetanthera africana. Place and Duration of Study: Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, VNS Group of Inst...
Open access
Research Article10.9734/bjpr/2016/31468
Introduction: Fatigue is one of the most prevalent phenomenon reported by post-partum mothers and have various effects on their physical, emotional and cognitive aspects. Back massage relaxation techniques are one of the most important non-pharmacological interventions to prevent...
Open access
Research Article10.9734/bjpr/2016/31509
Aim of Study: This study was designed to evaluate the hypolipidemic action of aqueous and ethanolic extracts of leaves of Allium schoenoprasum in albino rats. Methodology: 500 g of dried leaves powder was initially soaked in 3 L of 99.9% ethanol for three days and after filtratio...
Open access
Research Article10.9734/bjpr/2016/31804
Celtis integrifolia Lam. plants also known as hackberries or nettle trees are widely spread in warm temperate region of African, Latin America and Asia. The aqueous leaf extract of Celtis integrifolia was obtained by soxhlet extraction using distilled water as a solvent. The aque...
Open access
Research Article10.9734/bjpr/2016/31222
Inflammation is often prolonged after sepsis, trauma and other acute pro-inflammatory events, particularly above the age of 80 years. Exposure to inflammation of inappropriate amplitude or duration is associated with a higher risk of delirium, anorexia, lethargy, low mood, weakne...
Open access
Research Article10.9734/bjpr/2016/31788
In the present study, the leaf explant cultured on a MS medium supplemented with BAP (4.44 μM) + NAA (0.98 μM) had the ability to induce more amount of green and friable callus. The 40 days old best grown callus was sub cultured on the combination of various concentrations of BAP...
Open access
Research Article10.9734/bjpr/2016/30425
Carbohydrate antigen 19–9 (CA 19–9) is a tumor–associated antigen, which is used in the diagnosis of pancreatic cancer but is also a marker of pancreatic tissue damage that might be caused by diabetes. The aim of this study was to evaluate serum CA19–9 levels in patients with typ...
Open access
Research Article10.9734/bjpr/2016/30808